Traumatic Ulcer
Susan Müller, DMD, MS
Key Facts
Terminology
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Chronic traumatic ulceration of oral mucosa with unique histopathologic features
Etiology/Pathogenesis
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Accidental trauma from biting or fractured teeth
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Riga-Fede disease
Clinical Issues
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Can occur anywhere in oral cavity
Microscopic Pathology
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Ulcer bed composed of granulation tissue with mixed chronic inflammatory cell infiltrate lymphocytes, histiocytes, neutrophils, and occasionally plasma cells
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Inflammation including scattered eosinophils extends into underlying muscle
Top Differential Diagnoses
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Recurrent aphthous stomatitis
TERMINOLOGY
Synonyms
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Traumatic ulcer with stromal eosinophilia
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Eosinophilic granuloma of tongue
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Traumatic granuloma
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Atypical histiocytic granuloma
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Riga-Fede disease
Definitions
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Chronic traumatic ulceration of oral mucosa with unique histopathologic features
ETIOLOGY/PATHOGENESIS
Mechanical Damage
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Accidental trauma from biting
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Fractured or malposed teeth
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Sharp foodstuffs
Self-Inflicted Wound
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Parafunctional habits
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Nocturnal clenching
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Tongue and lip biting
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Riga-Fede disease
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Ulceration of ventral tongue caused by tongue thrusting
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Occurs in infants with natal or neonatal teeth
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Electrical and thermal injury
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