Thrombocytopenia Thrombocytopenia is a low platelet count below 150×109/L. The causes of a low platelet count can be grouped according to reduced production, decreased survival or sequestration in the spleen. Causes Reduced Production • Aplastic anaemia • Drugs, e.g. tolbutamide, alcohol, cytotoxic agents • Viral infections, e.g. EBV, CMV • Myelodysplasia • Bone marrow infiltration, e.g. carcinoma, leukaemia, myeloma, myelofibrosis • Megaloblastic anaemia • Hereditary thrombocytopenia Decreased Platelet Survival Immune • ITP • Drugs, e.g. heparin, quinine, sulphonamides, penicillins, gold • Infections • Post-transfusion Non-Immune • Disseminated intravascular coagulation (DIC) • Thrombotic thrombocytopenic purpura • Haemolytic uraemic syndrome Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading... Related Related posts: Incontinence Syncope Haematemesis Disorders Stay updated, free articles. Join our Telegram channel Join Tags: Churchills Pocketbook of Differential Diagnosis May 18, 2017 | Posted by admin in GENERAL & FAMILY MEDICINE | Comments Off on Thrombocytopenia Full access? Get Clinical Tree Get Clinical Tree app for offline access Get Clinical Tree app for offline access
Thrombocytopenia Thrombocytopenia is a low platelet count below 150×109/L. The causes of a low platelet count can be grouped according to reduced production, decreased survival or sequestration in the spleen. Causes Reduced Production • Aplastic anaemia • Drugs, e.g. tolbutamide, alcohol, cytotoxic agents • Viral infections, e.g. EBV, CMV • Myelodysplasia • Bone marrow infiltration, e.g. carcinoma, leukaemia, myeloma, myelofibrosis • Megaloblastic anaemia • Hereditary thrombocytopenia Decreased Platelet Survival Immune • ITP • Drugs, e.g. heparin, quinine, sulphonamides, penicillins, gold • Infections • Post-transfusion Non-Immune • Disseminated intravascular coagulation (DIC) • Thrombotic thrombocytopenic purpura • Haemolytic uraemic syndrome Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading... Related Related posts: Incontinence Syncope Haematemesis Disorders Stay updated, free articles. Join our Telegram channel Join Tags: Churchills Pocketbook of Differential Diagnosis May 18, 2017 | Posted by admin in GENERAL & FAMILY MEDICINE | Comments Off on Thrombocytopenia Full access? Get Clinical Tree