Radial Scar/Complex Sclerosing Lesion Savitri Krishnamurthy, MD Key Facts Clinical Issues Most radial sclerosing lesions are microscopic findings detected following investigation of mammographically found density lesions Risk factor for subsequent…
Warthin Tumor Rose Anton, MD Key Facts Cytopathology Aspiration may yield thick, tan-brown fluid Combination of oncocytic-appearing epithelial cells and mature lymphocytes Squamous (metaplastic) cells may be identified Top Differential…
Metastatic Malignancies (Carcinoma, Melanoma) Rose Anton, MD Key Facts Cytopathology Hyperchromatic nuclei with sharp angulations in squamous cell carcinoma Dense/glassy cytoplasm in squamous cell carcinoma Vesicular chromatin and prominent nucleoli…
Rosai-Dorfman Disease Rose Anton, MD John M. Stewart, MD, PhD Key Facts Clinical Issues Usually asymptomatic adenopathy in young patients Spontaneous regression occurs in most patients No specific therapy is…
Thyroid Lymphoma Susan L. Haley, MD Key Facts Clinical Issues Generally associated with lymphocytic thyroiditis Cytopathology Hypercellular aspirate of noncohesive lymphoid cells Lymphoglandular bodies are usually present May see lymphoepithelial…
Suspicious for Hürthle Cell Neoplasm Mojgan Amrikachi, MD Key Facts Clinical Issues 3-15% of thyroid neoplasms F:M = 3:1 Cytopathology Crowded groups, small clusters, or dyscohesive cells Polygonal cells with…
Other Malignancies in Urinary Cytology Rose Anton, MD Nour Sneige, MD Key Facts Top Differential Diagnoses Small cell carcinoma: Resembles small cell carcinoma of other sites; necrosis present; neuroendocrine markers…
Immunocytochemistry, Histochemistry, and Other Ancillary Techniques Donna M. Coffey, MD GMS special stain of a pleural effusion highlights numerous fungal organisms morphologically consistent with Aspergillus. Special stains can be performed…
Superficial Aspiration Technique Rose Anton, MD (A) Fine-needle aspiration (FNA) may be performed in a physician’s office, clinic, radiology, or at the bedside. A room dedicated for performing FNAs is…
Squamous Cell Carcinoma of Urinary Bladder Rose Anton, MD Nour Sneige, MD Key Facts Clinical Issues Varies with geographic region (incidence higher in areas of endemic schistosomiasis) Hematuria Radical cystectomy…
