Steatorrhoea refers to the passing of excessive amounts of fat in the faeces. The causes are listed below, according to pathogenesis. Patients with steatorrhoea often pass bulky, sticky and greasy stool that floats and is often difficult to flush away. Diarrhoea is the usual accompanying symptom (p. 100) for most of the causes. Jaundice with pale stools and dark urine implies obstruction to the flow of bile, which is essential for the absorption of fat and fat-soluble vitamins. The causes and diagnostic approach to jaundice are found on p. 256. Vague epigastric abdominal pain experienced by patients with chronic pancreatitis may radiate to the back and is usually worse with food. Epigastric pain exacerbated by food may be a symptom of Zollinger–Ellison syndrome, which results in excessive gastric acid production (lowering the pH of gastric chyme), inactivating lipase. It usually presents with symptoms of peptic ulceration refractory to medical treatment. Abdominal pains associated with Crohn’s disease are often felt in the right iliac fossa due to regional ileitis. Patients with coeliac disease may also suffer with growth retardation and nutritional deficiencies causing anaemia and muscle wasting. Other symptoms may include bone fracture due to demineralisation, cerebellar ataxia and peripheral neuropathy. Joint pains, pyrexia, skin pigmentation and peripheral lymphadenopathy are among the varied symptoms of Whipple’s disease, resulting from infection with the bacterium Tropheryma whipplei. Steatorrhoea is the primary manifestation of intestinal lymphoma. It may be accompanied by abdominal pains and pyrexia and occasionally present with intestinal obstruction. Mouth ulcers, perianal abscesses, right iliac fossa pains and blood PR are some of the symptoms experienced by patients with Crohn’s disease. Ataxia and night blindness from retinitis pigmentosa may result from abetalipoproteinaemia, which is caused by the absence of apolipoprotein B and therefore results in defective chylomicron formation.
Steatorrhoea
History
Abdominal pain
Associated symptoms
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