Squamous/Adenosquamous Carcinoma, Pancreas



Squamous/Adenosquamous Carcinoma, Pancreas


Mari Mino-Kenudson, MD









A primary adenosquamous cell carcinoma in the tail of the pancreas shows a relatively well-demarcated tanwhite to yellow solid mass with a cystic component.






Adenosquamous cell carcinoma of the pancreas demonstrates islands of malignant squamous cells with keratinization image adjacent to PanIN-3 involving an interlobular duct image.


TERMINOLOGY


Definitions



  • Uncommon variant of pancreatic cancer with both glandular and squamous differentiation



    • Pure squamous cell carcinoma of pancreas is vanishingly rare


ETIOLOGY/PATHOGENESIS


Neoplastic



  • A few hypotheses attempt to explain origin of squamous component



    • Squamous metaplasia of pancreatic duct epithelium


    • Both components derive from common progenitor


CLINICAL ISSUES


Epidemiology

Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Squamous/Adenosquamous Carcinoma, Pancreas
Premium Wordpress Themes by UFO Themes
%d bloggers like this: