Chapter 41 Scientific tests
Blood Tests (Table 41.1)
Test | Normal Range | |
Males | Females | |
FULL BLOOD COUNT | ||
Red blood cells | 4.5–6.5 1012/L | 3.8–5.0 1012/L |
Haemoglobin | 13–18 g/100 mL | 11.5–16.5 g/100 mL |
Hct | 45–52% | 37–48% |
MCV | 80–96 femtoL | 80–96 femtoL |
MCH | 27–32 pg | 27–32 pg |
MCHC | 32–36 g/dL | 32–36 g/dL |
RDW | 11–15% | 11–15% |
White blood cell count | 4–11 109/L | 4–11 109/L |
Neutrophils | 2.0–7.5 109/L | 2.0–7.5 109/L |
Lymphocytes | 1.3–4.0 109/L | 1.3–4.0 109/L |
Monocytes | 0.2–0.8 109/L | 0.2–0.8 109/L |
Eosinophils | 0.04–0.44 109/L | 0.04–0.44 109/L |
Basophils | 0.0–0.109/L | 0.0–0.109/L |
Platelets | 150–440 109/L | 150–440 109/L |
AUTOMATED WHITE CELL DIFFERENTIAL | ||
Segmented neutrophils | 34–75% | 34–75% |
Band neutrophils | 8% | 8% |
Lymphocytes | 12–50% | 12–50% |
Monocytes | 3–15% | 3–15% |
Eosinophils | 5% | 5% |
Basophils | 3% | 3% |
Prothrombin time | 10–15 s | 10–15 s |
LIVER FUNCTION TESTS | ||
Bilirubin | 0–21 micromol/L | 0–21 micromol/L |
Serum alkaline phosphatase | 20–125 iu/L | 20–125 iu/L |
ALT/SGPT | 0–40 iu/L | 0–40 iu/L |
ALT/SGOT | 0–48 /L | 0–48 IU/L |
GGT | 0–45 IU/L | 0–45 IU/L |
Total serum protein | 59–82 g/L | 59–82 g/L |
Blood Lipids | ||
Total cholesterol | >200 mg/dL | >200 mg/dL |
HDL | <37 mg/dL | <47 mg/dL |
LDL | >130 mg/dL | >130 mg/dL |
Triglycerides | >150 mg/dL | >150 mg/dL |
Ferritin | 18–270 ng/mL | 18–160 ng/mL |
Fasting glucose | 60–109 mg/dL | 60–109 mg/dL |
UREA AND ELECTROLYTES | ||
Serum sodium | 133–145 mmol/L | 133–145 mmol/L |
Serum potassium | 3.5–5.3 mmol/L | 3.5–5.3 mmol/L |
Serum urea | 2.5–6.6 mmol/L | 2.5–6.6 mmol/L |
Serum creatinine | 45–110 lmol/L | 45–110 lmol/L |
Erythrocyte sedimentation rate (ESR) | >15 mm/h | >20 mm/h |
Rheumatoid factor | 0–35 IU/mL | 0–35 IU/mL |
HORMONAL LEVELS | ||
Serum TSH | 0.3–3 mIU/L | 0.3–3 mIU/L |
Serum thyroxine T4 (protein bound) | 4.6–12 lg/dL | 4.6–12 lg/dL |
Free T4 (FT4) | 0.7–1.9 ng/dL | 0.7–1.9 ng/dL |
Serum triiodothyronine (protein bound) | 80–180 ng/dL | 80–180 ng/dL |
Free T3 (FT3) | 230–619 pg/d | 230–619 pg/d |
Serum prolactin | N/A | 0 to 20 ng/mL |
Serum LH | N/A | 5–20 mIU/mL |
Serum FSH | N/A | 5 –30 mIU/mL |
Serum FSH after menopause | N/A | 50–100 mIU/mL |
KEY VITAMIN AND METABOLITES | ||
Serum B12 | 150–600 pmol/L | 150–600 pmol/L |
Red cell folate | 360–1400 nmol/L | 360–1400 nmol/L |
Homocysteine | 5–15 lmol/L | 5–15 lmol/L |
METALS | ||
Copper | >20 mg/dL | >20 mg/dL |
Urinary copper | <100 μg/24h | <100 μg/24h |
Full Blood Count
This is performed if there is:
Babies under 1 year and pregnant women can also be screened this way.
Haematocrit (Hct)
• If raised, can indicate reduced plasma volume, possibly due to dehydration, e.g. drug (diuretic) or alcohol induced. Might also indicate increased red cell mass due to certain types of tumours.
• Mean Cell (Corpuscular) Volume (MCV)
• Low in microcytic anaemia, found in iron-deficient anaemia (see Chapter 28 ‘Blood disorders’, p. 209).
• High in macrocytic anaemia, found in pernicious anaemia (see Chapter 28 ‘Blood disorders’, p. 210).
• Mean Corpuscular Cell Haemoglobin Concentration (MCHC)
• Normal in macrocytic (normochromic) anaemias: this is because although the cell size is larger than normal the amount of haemoglobin is high therefore making the concentration normal:
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