Reactive Nodular Fibrous Pseudotumor of Mesentery



Reactive Nodular Fibrous Pseudotumor of Mesentery


Elizabeth A. Montgomery, MD









Hematoxylin & eosin shows low magnification of a reactive nodular fibrous pseudotumor involving the mesentery extending up into the deep gastric submucosa.






Hematoxylin & eosin shows a higher magnification of the lesion. There are a few plasma cells along with fibroblastic cells and a collagenized background.


TERMINOLOGY


Definitions



  • Lesion of mesentery composed of stellate and spindle-shaped cells arranged in collagen-rich stroma with lymphoid aggregates


CLINICAL ISSUES


Epidemiology



  • Incidence



    • Rare


  • Age



    • Predominantly adults


  • Gender



    • No predominance


Presentation



  • Obstruction


  • Frequent history of prior operations, evidence of prior bowel perforation, or history of pancreatitis


  • Some patients have multiple nodules



    • Some lesions associated with foreign bodies


  • Most in small bowel (ileal) mesentery



    • Also in colon mesentery and in bed of area of prior pancreatitis


Treatment



  • Surgical excision


Prognosis



  • Excellent; benign process

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Reactive Nodular Fibrous Pseudotumor of Mesentery
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