Prurigo Nodularis

Prurigo Nodularis

Christine J. Ko, MD

Low-power view of prurigo nodularis shows prominent hyperkeratosis image, parakeratosis, and hypergranulosis image overlying irregular acanthosis image with vertical streaking of collagen in the papillary dermis.

High magnification of prurigo nodularis shows hypergranulosis image. There is vertical streaking of collagen bundles present in the papillary dermis image, a finding seen in both prurigo nodularis and lichen simplex chronicus.



  • Prurigo nodularis (PN)


  • Pruritic nodules

  • Generally on extensor surfaces of extremities

  • Secondary to chronic rubbing/scratching

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Prurigo Nodularis

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