14 Protein transport into mitochondria and nuclei
Protein incorporation into mitochondria
Nearly all mitochondrial proteins are synthesized in the cytoplasm and taken up into the mitochondrion post-translationally. Proteins are targeted to mitochondria by short targeting signals, which may be located at the N-terminal or internally within the polypeptide chain. Receptors in the outer mitochondrial membrane recognize the signal and direct the proteins to the import machinery (Fig. 3.14.1
Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree
