Primary Oxalosis



Primary Oxalosis


Shane M. Meehan, MBBCh










Hematoxylin & eosin using partially polarized light shows abundant anisotropic calcium oxalate in the cortex of a 4-month-old male with primary oxalosis type 1.






Refractile, pale yellow, calcium oxalate crystals are seen, some of which are in giant cells image in the renal cortex.


TERMINOLOGY


Abbreviations



  • Primary oxalosis (PO)



    • Type 1 (PO1), type 2 (PO2)


Synonyms



  • Primary hyperoxaluria (PH), primary hyperoxalemia


Definitions



  • Oxalate overproduction due to gene mutations affecting enzymes that catalyze glyoxylate breakdown, with systemic calcium oxalate deposition


ETIOLOGY/PATHOGENESIS


Hereditary Disorder

Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Primary Oxalosis
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