Polyvinylpyrrolidone Storage Disease



Polyvinylpyrrolidone Storage Disease


Cyril Fisher, MD, DSc, FRCPath










Low-magnification image of PVP storage disease shows soft tissue infiltrated by sheets and nests of uniform macrophages containing basophilic material in their cytoplasm.






Higher magnification shows histiocytic infiltrate with “bubbly” basophilic cytoplasm containing PVP and circular spaces image. The nuclei image are small and lack atypia and mitotic activity.


TERMINOLOGY


Abbreviations



  • Polyvinylpyrrolidone (PVP) storage disease


Synonyms



  • Mucicarminophilic histiocytosis


  • Polyvinylpyrrolidone granuloma


Definitions



  • Phagocytic foreign body-type reactive condition in which PVP is deposited and retained in tissue

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Polyvinylpyrrolidone Storage Disease
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