Pear: Opuntia ficus-indica (L.) Mill., O. streptacantha Lem., and related species


Prickly Pear


Opuntia ficus-indica (L.) Mill., O. streptacantha Lem., and related species


Family:


Cactaceae


Other common names:


Indian fig; nopal; paddle cactus; tuna


Botanical drug used:


Cladode


Main chemical compounds:


The genus is rich in fibre and also in polysaccharides, especially the younger cladodes. A mucilage constituting up to 14% of the cladode dry weight is produced, especially by younger cladodes and also by the fruits, and consists of chains of (14)-linked β-D-galacturonic acid and R(1-2)-linked L-rhamnose residues (Stinzing and Carle 2005).


Clinical evidence:


Overall, some – so far still limited – evidence points to the potential of a chemically well characterised extract in the management of pre-diabetic conditions and in glucose management.


Antidiabetic effects:


Initial studies in Mexico showed encouraging hypoglycaemic effects in human diabetic and normal subjects (Frati-Munari et al. 1991; Frati-Munari et al. 1988). More recently, a small (verum—n = 15, placebo—n = 14) double-blind, placebo-controlled study used 200 mg of a chemically characterised extract over a 16-week period. An oral glucose tolerance test (OGTT) was also included, with a 400 mg dose of an O. ficus-indica preparation given 30 min before orally ingesting a 75 g glucose drink. The authors demonstrated acute blood-glucose-lowering effects and the long-term safety of the proprietary product used (Godard et al. 2010).


Stimulation of glycogen synthesis:


An O. ficus-indica

Stay updated, free articles. Join our Telegram channel

Nov 25, 2016 | Posted by in PHARMACY | Comments Off on Pear: Opuntia ficus-indica (L.) Mill., O. streptacantha Lem., and related species

Full access? Get Clinical Tree

Get Clinical Tree app for offline access