Today, pain is the most common symptom for which patients report using medical cannabis. The key to effectively using cannabis for pain is finding the optimal dose. Since the body uses its endocannabinoid system to modulate overall pain levels and signaling, dose becomes crucial to remain in the “sweet spot” of sustained pain relief. It may be that some painful conditions, including fibromyalgia and migraine, may actually be linked to a deficiency of endocannabinoids.124 In such a situation, cannabis is used like a vitamin to supplement this deficiency and restore balance—a novel treatment approach. There are different types of common pain. Acute pain typically persists until the painful stimulus is removed or physical damage has healed. Chronic pain is pain that lasts for more than three months, as found with conditions such as cancer or arthritis. Neuropathic pain is caused by damage to nerve tissues, often in the extremities from conditions such as diabetes or as a side effect of drugs, including chemotherapy agents. Neuropathy often produces a “pins and needles” or burning sensation. Pruritus, a severe itching, has many similarities to pain and can be closely associated with neuropathic pain, although pain inhibits itching. EFFECTIVENESS
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