Figure 15-10 Standardized incidence ratios (SIRs) for cancers at various sites in first-degree relatives (child or sibling) of an affected person. A SIR is similar to the relative risk ratio (λr) that is based on prevalence of disease (as described in Chapter 8), except SIR is the ratio of the incidence of cases of cancer in relatives divided by the number expected from the incidence in an age-matched group in the general population. Error bars reflect 95% confidence limits on the SIRs. See Sources & Acknowledgments.
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