Chapter 81 Multiple System Organ Failure
When asked to assess a patient who is likely to have multisystem organ failure (MSOF), I specifically look to uncover any infectious or inflammatory source that may have set off the process. This requires a detailed hx and a complete physical examination. Given the patient’s clinical situation, a detailed hx may be difficult to obtain. Accordingly, I make it a point to review all hospital records from this and previous admissions, and I talk to family members who might be informed about recent events. I carefully assess all of the patient’s comorbidities, including hx of tobacco (COPD) and alcohol (cirrhosis) use, which may play an important role in ultimate outcome.