Multicentric Reticulohistiocytosis



Multicentric Reticulohistiocytosis


David Cassarino, MD, PhD










Low magnification of MCR shows a nodular proliferation of enlarged histiocytic cells in the dermis. There is a very thin grenz zone image, and the epidermis shows flattening of the rete ridges.






Higher magnification of MCR shows a proliferation of numerous enlarged histiocytic-appearing cells image associated with a background mixed inflammatory infiltrate containing scattered eosinophils image.


TERMINOLOGY


Abbreviations



  • Multicentric reticulohistiocytosis (MCR)


Synonyms



  • Giant cell reticulohistiocytosis


  • Reticulohistiocytosis of skin and synovia


Definitions



  • Proliferation of large histiocytes with dense eosinophilic cytoplasm involving multiple organs

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Multicentric Reticulohistiocytosis
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