Molecular Factor |
Chromosomal Location |
Definition/Alternative Names |
Chapters |
β-catenin (see CTNNB1) |
|
|
|
10q, alterations of |
10q |
|
Growth Hormone-producing Adenoma |
10q11.2 |
10q11.2 |
RET |
Familial Thyroid Carcinoma; Multiple Endocrine Neoplasia Type 2; Parathyroid Adenoma; Parathyroid Carcinoma; Primary Chief Cell Hyperplasia |
10q23 |
10q23 |
|
Merkel Cell Carcinoma |
10q23.31 |
10q23.31 |
PTEN |
Familial Thyroid Carcinoma; Carney Complex |
11p15 |
11p15 |
IGF2 |
Ectopic (Paraneoplastic) Syndromes |
11q, alterations of |
11q |
|
Growth Hormone-producing Adenoma; Neuroblastoma and Related Tumors |
11q, loss of |
11q |
|
Pancreatic Endocrine Neoplasms; Solid-Pseudopapillary Tumor of Pancreas |
11q13 |
11q13 |
MEN1 |
Multiple Endocrine Neoplasia Type 1; Pancreatic Endocrine Neoplasms; Parathyroid Adenoma; Parathyroid Carcinoma; Primary Chief Cell Hyperplasia |
11q23 |
11q23 |
SDHD |
Pheochromocytoma and Extraadrenal Paraganglioma |
12q24 |
12q24 |
PTPN11 |
Carney Complex |
13q, alterations of |
13q |
|
Growth Hormone-producing Adenoma |
13q, gain of |
13q |
|
Solid-Pseudopapillary Tumor of Pancreas |
14q, alterations of |
14q |
|
Familial Thyroid Carcinoma |
16p, alterations of |
16p |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
17p, alterations of |
17p |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
17p13.1 |
17p13.1 |
TP53 |
Adrenal Cortical Carcinoma |
17p13 |
17p13 |
|
Pancreatic Endocrine Neoplasms |
17q, gain of |
17q |
|
Solid-Pseudopapillary Tumor of Pancreas |
17q11.2 |
17q11.2 |
NF1 |
Pheochromocytoma and Extraadrenal Paraganglioma; Neurofibromatosis Type 1 (NF1) |
17q22-24 |
17q22-24 |
PRKAR1A |
Carney Complex; Familial Thyroid Carcinoma; Primary Pigmented Nodular Adrenal Disease |
18q, alterations of |
18q |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
18q, gain of |
18q |
|
Merkel Cell Carcinoma |
19p, alterations of |
19p |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
19p13 |
19p13 |
|
Familial Thyroid Carcinoma; Follicular Adenoma |
19p13.3 |
19p13.3 |
LKB1 |
Carney Complex |
1p, alterations of |
1p |
|
Merkel Cell Carcinoma; Neuroblastoma and Related Tumors; Undifferentiated/Anaplastic Thyroid Carcinoma |
1p, loss of |
1p |
|
Merkel Cell Carcinoma |
1q, alterations of |
1q |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
1q, gain of |
1q |
|
Solid-Pseudopapillary Tumor of Pancreas |
1q21 |
1q21 |
SDHC |
Familial Thyroid Carcinoma; Papillary Thyroid Carcinoma |
1q21-q31 |
1q21-q31 |
HRPT2 |
Primary Chief Cell Hyperplasia |
20q13.3 |
20q13.3 |
GNAS1 |
McCune-Albright Syndrome |
22q, alterations of |
22q |
|
Pancreatic Endocrine Neoplasms; Undifferentiated/Anaplastic Thyroid Carcinoma |
22q12 |
22q12 |
Ewing sarcoma breakpoint region 1 |
Primary Thyroid Ewing Sarcoma, Thyroid |
2p21 |
2p21 |
|
Follicular Adenoma |
2q15-16 |
2q15-16 |
|
Primary Pigmented Nodular Adrenal Disease |
2q21 |
2q21 |
|
Familial Thyroid Carcinoma |
2q31-2q35 |
2q31-2q35 |
PDE11A |
Primary Pigmented Nodular Adrenal Disease |
3q, alterations of |
3q |
|
Merkel Cell Carcinoma |
3q13.3-21 |
3q13.3-21 |
CASR |
Primary Chief Cell Hyperplasia |
5p, gain of |
5p |
|
Merkel Cell Carcinoma |
5q21 |
5q21 |
APC |
Familial Thyroid Carcinoma; Papillary Thyroid Carcinoma |
7q21-34 |
7q21-34 |
SLC26A4 |
Familial Thyroid Carcinoma |
8p11-12 |
8p11-12 |
WRN |
Familial Thyroid Carcinoma |
8q, gain of |
8q |
|
Solid-Pseudopapillary Tumor of Pancreas |
9p, alterations of |
9p |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
9q, gain of |
9q |
|
Pancreatic Endocrine Neoplasms |
AIP |
11q13.3 |
aryl hydrocarbon receptor interacting protein |
Multiple Endocrine Neoplasia Type 1; Pituitary Carcinoma |
AKT1 |
14q32.32 |
v-akt murine thymoma viral oncogene homolog 1 |
Molecular Pathology of Thyroid Neoplasms |
APC |
5q21 |
adenomatosis polyposis coli |
Familial Thyroid Carcinoma; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Cribriform-Morular Variant |
BRAF |
7q34 |
v-raf murine sarcoma viral oncogene homolog B1 |
Follicular Adenoma; Hashimoto Thyroiditis; Hyalinizing Trabecular Tumor; Mixed Medullary and Follicular Cell Carcinoma; Molecular Pathology of Thyroid Neoplasms; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Classical Variant; Papillary Thyroid Carcinoma, Columnar Cell Variant; Papillary Thyroid Carcinoma, Cribriform-Morular Variant; Papillary Thyroid Carcinoma, Diffuse Sclerosing Variant; Papillary Thyroid Carcinoma, Follicular Variant; Papillary Thyroid Carcinoma, Hobnail Variant; Papillary Thyroid Carcinoma, Oncocytic Variant; Papillary Thyroid Carcinoma, Tall Cell Variant; Papillary Thyroid Carcinoma, Warthin-like Variant; Poorly Differentiated Thyroid Carcinoma; Sclerosing Mucoepidermoid Carcinoma with Eosinophilia; Solid Cell Nests; Struma Ovarii, Struma Carcinoid, and Malignant Struma Ovarii; Undifferentiated/Anaplastic Thyroid Carcinoma |
BRAF/AKAP9 |
inv(7)(q21q34) |
|
Molecular Pathology of Thyroid Neoplasms; Papillary Thyroid Carcinoma |
BRCA2 |
13q12.3 |
breast cancer 2, early onset |
Parathyroid Carcinoma |
CASR |
3q13.3-21 |
calcium-sensing receptor |
Primary Chief Cell Hyperplasia |
CCND1 |
11q13 |
cyclin D1; B-cell CLL/lymphoma 1; BCL1 |
Parathyroid Adenoma; Parathyroid Carcinoma; Primary Chief Cell Hyperplasia |
CDKN1B |
12p13.1-p12 |
cyclin-dependent kinase inhibitor 1B; CDKN4; p27/KIP1 |
ACTH-producing Adenoma; Pituitary Adenomas |
CDKN1C |
11p15.5 |
cyclin-dependent kinase inhibitor 1C; p57/KIP2 |
Adrenal Cortical Carcinoma |
CDKN2A |
9p21 |
cyclin-dependent kinase inhibitor 2A; p16; p16INK4; ARF |
ACTH-producing Adenoma; Growth Hormone-producing Adenoma; Pancreatic Endocrine Neoplasms; Pituitary Adenomas; Prolactin-producing Adenoma; Undifferentiated/Anaplastic Thyroid Carcinoma |
CDKN2C |
1p32 |
cyclin-dependent kinase inhibitor 2C; p18 |
ACTH-producing Adenoma; Pituitary Adenomas |
Chromosome 1, alterations of |
1 |
|
Neuroblastoma and Related Tumors |
Chromosome 1, gain of |
1 |
|
Merkel Cell Carcinoma |
Chromosome 1, loss of |
1 |
|
Pancreatic Endocrine Neoplasms |
Chromosome 11, alterations of |
11 |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
Chromosome 13, loss of |
13 |
|
Merkel Cell Carcinoma |
Chromosome 17, alterations of |
17 |
|
Neuroblastoma and Related Tumors |
Chromosome 20, gain of |
20 |
|
Merkel Cell Carcinoma |
Chromosome 5, alterations of |
5 |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
Chromosome 5, gain of |
5 |
|
Merkel Cell Carcinoma |
Chromosome 6, gain of |
6 |
|
Merkel Cell Carcinoma |
Chromosome 8, alterations of |
8 |
|
Undifferentiated/Anaplastic Thyroid Carcinoma |
CpG island methylation |
|
|
Growth Hormone-producing Adenoma; Prolactin-producing Adenoma |
CTNNB1 |
11q13 |
catenin (cadherin-associated protein), beta 1; β-catenin |
Craniopharyngioma, Pituitary Gland; Molecular Pathology of Thyroid Neoplasms; Papillary Thyroid Carcinoma, Cribriform-Morular Variant; Papillary Thyroid Carcinoma, Follicular Variant; Parathyroid Adenoma; Parathyroid Carcinoma; Poorly Differentiated Thyroid Carcinoma; Primary Chief Cell Hyperplasia; Solid-Pseudopapillary Tumor of Pancreas; Undifferentiated/Anaplastic Thyroid Carcinoma |
Cyclin D1 (see CCND1) |
|
|
|
DAPK |
9q34.1 |
death-associated protein kinase |
Growth Hormone-producing Adenoma |
DAX1 |
Xp21.3 |
NR0B1 |
Adrenal Cytomegaly |
EBER |
|
EBV-encoded small nuclear RNA; EBER-1 |
Carcinoma Showing Thymus-like Differentiation |
EWSR1 |
22q12 |
Ewing sarcoma breakpoint region 1 |
Primary Thyroid Ewing Sarcoma, Thyroid |
EWSR1-FLI1 |
t(11;22)(q24;q12) |
|
Neuroblastoma and Related Tumors; Primary Thyroid Ewing Sarcoma, Thyroid |
FAS |
10q24.1 |
TNF receptor superfamily, member 6; CD95 |
Lymphoma, Thyroid |
FGFR4 |
5q35.1-qter |
fibroblast growth factor receptor 4 |
ACTH-producing Adenoma; Gonadotropin-producing Adenoma; Null Cell Adenoma; Pituitary Carcinoma; Plurihormonal Adenoma |
GASC1 |
9p24.1 |
gene amplified in squamous cell carcinoma 1; KDM4C |
Adrenal Cortical Hyperplasia |
GNAS |
20q13 |
GNAS complex locus |
Carney Complex; Follicular Thyroid Carcinoma; Growth Hormone-producing Adenoma; Hyperparathyroidism-Jaw Tumor Syndrome; McCune-Albright Syndrome; McCune-Albright Syndrome; Neurofibromatosis Type 1 (NF1); Pituitary Adenomas |
GNAS1 (see GNAS) |
|
|
|
H19 |
11p15.5 |
imprinted maternally expressed transcript (non-protein coding) |
Adrenal Cortical Carcinoma |
HMGA2 |
12q15 |
high mobility group AT-hook 2; HMGIC |
Prolactin-producing Adenoma |
HRAS |
11p15.5 |
v-Ha-ras Harvey rat sarcoma viral oncogene homolog |
Follicular Adenoma; Follicular Thyroid Carcinoma; Hashimoto Thyroiditis; Merkel Cell Carcinoma; Molecular Pathology of Thyroid Neoplasms; Papillary Thyroid Carcinoma, Follicular Variant; Pituitary Carcinoma; Poorly Differentiated Thyroid Carcinoma |
HRPT2 |
1q21-q31 |
hyperparathyroidism 2 |
Hyperparathyroidism-Jaw Tumor Syndrome; McCune-Albright Syndrome; Multiple Endocrine Neoplasia Type 1; Parathyroid Adenoma; Parathyroid Atypical Adenoma; Primary Chief Cell Hyperplasia |
IGF2 |
11p15 |
insulin-like growth factor 2; IGF-II |
Adrenal Cortical Carcinoma; Ectopic (Paraneoplastic) Syndromes |
Ikaros |
7p13-p11.1 |
IKAROS family zinc finger 1; IKZF1 |
ACTH-producing Adenoma; Gonadotropin-producing Adenoma; Null Cell Adenoma; Pituitary Adenomas; Plurihormonal Adenoma |
inv(10)(q11.2q21) |
inv(10)(q11.2q21) |
|
Papillary Thyroid Carcinoma |
KRAS |
12p12.1 |
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
Hashimoto Thyroiditis; Molecular Pathology of Thyroid Neoplasms; Pancreatic Endocrine Neoplasms; Papillary Thyroid Carcinoma, Follicular Variant; Poorly Differentiated Thyroid Carcinoma; Solid-Pseudopapillary Tumor of Pancreas; Spindle Cell Tumor with Thymus-like Differentiation |
LKB1 |
19p13.3 |
liver kinase B1; STK11 |
Carney Complex |
MDR1 |
7q21.12 |
multidrug resistence protein 1 |
Adrenal Cortical Carcinoma |
MEN1 |
11q13 |
multiple endocrine neoplasia I |
ACTH-producing Adenoma; Adrenal Cortical Carcinoma; Adrenal Cortical Hyperplasia; Growth Hormone-producing Adenoma; Hyperparathyroidism-Jaw Tumor Syndrome; Multiple Endocrine Neoplasia Type 1; Multiple Endocrine Neoplasia Type 2; Pancreatic Endocrine Neoplasms; Parathyroid Adenoma; Parathyroid Carcinoma; Pituitary Adenomas; Pituitary Carcinoma; Primary Chief Cell Hyperplasia; Prolactin-producing Adenoma; Solid-Pseudopapillary Tumor of Pancreas |
MGMT |
10q26 |
O-6-methylguanine-DNA methyltransferase |
Plurihormonal Adenoma |
MYC |
8q24 |
v-myc myelocytomatosis viral oncogene homolog |
Adrenal Cortical Carcinoma; Primary Thyroid Ewing Sarcoma, Thyroid |
NF1 |
17q11.2 |
neurofibromin 1 |
Familial Paraganglioma-Pheochromocytoma; Multiple Endocrine Neoplasia Type 2; Neurofibromatosis Type 1 (NF1); Neuronal Cell Tumors, Pituitary Gland; Pancreatic Endocrine Neoplasms; Pheochromocytoma and Extraadrenal Paraganglioma |
NF2 |
22q12.2 |
neurofibromin 2 |
Neurofibromatosis Type 1 (NF1); Neuronal Cell Tumors, Pituitary Gland |
N-Myc |
2p24.3 |
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived |
Composite Tumor, Adrenal Glands; Neuroblastoma and Related Tumors |
NRAS |
1p13.2 |
neuroblastoma RAS viral (v-ras) oncogene homolog |
Follicular Adenoma; Follicular Thyroid Carcinoma; Hashimoto Thyroiditis; Molecular Pathology of Thyroid Neoplasms; Papillary Thyroid Carcinoma, Follicular Variant; Poorly Differentiated Thyroid Carcinoma |
NTRK1 |
1q22 |
neurotrophic tyrosine kinase, receptor, type 1 |
Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Classical Variant; Papillary Thyroid Carcinoma, Follicular Variant; Poorly Differentiated Thyroid Carcinoma |
P16 (see CDKN2A) |
|
|
|
P18 (see CDKN2C) |
|
|
|
P53 (see TP53) |
|
|
|
P57/KIP2 (see CDKN1C) |
|
|
|
PAX8 |
2q13 |
paired box 8 |
Follicular Thyroid Carcinoma; Molecular Pathology of Thyroid Neoplasms |
PAX8/PPARγ |
t(2;3)(q13;p25) |
|
Follicular Thyroid Carcinoma; Molecular Pathology of Thyroid Neoplasms |
PAX-FOXO1 |
|
|
Neuroblastoma and Related Tumors |
PDE11A |
2q31-2q35 |
phosphodiesterase 11A |
Adrenal Cortical Hyperplasia; Primary Pigmented Nodular Adrenal Disease |
PDE8B |
5q13.3 |
phosphodiesterase 8B |
Primary Pigmented Nodular Adrenal Disease |
PDS (see SLC26A4) |
|
|
|
PIK3CA |
3q26.3 |
phosphoinositide-3-kinase, catalytic, alpha polypeptide |
Follicular Thyroid Carcinoma; Molecular Pathology of Thyroid Neoplasms |
POMC |
2p23.3 |
proopiomelanocortin |
Ectopic (Paraneoplastic) Syndromes |
PPARγ |
3p25 |
peroxisome proliferator-activated receptor gamma; PPARG |
Follicular Thyroid Carcinoma; Papillary Thyroid Carcinoma, Follicular Variant |
PRKAR1A |
17q22-24 |
protein kinase, cAMP-dependent, regulatory, type I, alpha; PRKAR1-α |
Adenomatous Nodules; Adrenal Cortical Hyperplasia; Carney Complex; Familial Thyroid Carcinoma; Follicular Adenoma; Follicular Thyroid Carcinoma; Growth Hormone-producing Adenoma; Pituitary Carcinoma; Primary Pigmented Nodular Adrenal Disease |
PTEN |
10q23.3 |
phosphotase and tensin homolog |
Adenomatous Nodules; Carney Complex; Familial Thyroid Carcinoma; Follicular Adenoma; Follicular Thyroid Carcinoma; Molecular Pathology of Thyroid Neoplasms; Multinodular Thyroid Hyperplasia; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Follicular Variant; Undifferentiated/Anaplastic Thyroid Carcinoma |
PTPN11 |
12q24 |
protein tyrosine phosphatase, non-receptor type 11 |
Carney Complex |
RAF |
3p25 |
v-raf-1 murine leukemia viral oncogene homolog 1 |
Molecular Pathology of Thyroid Neoplasms |
RAS |
|
Rat sarcoma oncogenes |
Ectopic (Paraneoplastic) Syndromes; Follicular Thyroid Carcinoma; Hyalinizing Trabecular Tumor; Molecular Pathology of Thyroid Neoplasms; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Follicular Variant; Papillary Thyroid Carcinoma, Hobnail Variant; Papillary Thyroid Carcinoma, Tall Cell Variant; Pheochromocytoma and Extraadrenal Paraganglioma; Struma Ovarii, Struma Carcinoid, and Malignant Struma Ovarii; Undifferentiated/Anaplastic Thyroid Carcinoma |
RB (see RB1) |
|
|
|
RB1 |
13q14.2 |
retinoblastoma 1 |
ACTH-producing Adenoma; Adrenal Cortical Carcinoma; Growth Hormone-producing Adenoma; Parathyroid Carcinoma; Pituitary Adenomas |
RET |
10q11.2 |
ret proto-oncogene |
C-cell Hyperplasia; Composite Tumor, Adrenal Glands; Familial Paraganglioma-Pheochromocytoma; Familial Thyroid Carcinoma; Medullary Thyroid Carcinoma; Mixed Medullary and Follicular Cell Carcinoma; Molecular Pathology of Thyroid Neoplasms; Multiple Endocrine Neoplasia Type 1; Multiple Endocrine Neoplasia Type 2; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Follicular Variant; Papillary Thyroid Carcinoma, Solid Variant; Parathyroid Adenoma; Parathyroid Carcinoma; Pheochromocytoma and Extraadrenal Paraganglioma; Primary Chief Cell Hyperplasia; Struma Ovarii, Struma Carcinoid, and Malignant Struma Ovarii |
RET/PTC |
|
|
Follicular Adenoma; Follicular Thyroid Carcinoma; Hashimoto Thyroiditis; Medullary Thyroid Carcinoma; Mixed Medullary and Follicular Cell Carcinoma; Molecular Pathology of Thyroid Neoplasms; Multiple Endocrine Neoplasia Type 2; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Classical Variant; Papillary Thyroid Carcinoma, Cribriform-Morular Variant; Papillary Thyroid Carcinoma, Follicular Variant; Papillary Thyroid Carcinoma, Hobnail Variant; Papillary Thyroid Carcinoma, Oncocytic Variant; Papillary Thyroid Carcinoma, Tall Cell Variant; Papillary Thyroid Carcinoma, Warthin-like Variant; Poorly Differentiated Thyroid Carcinoma |
RET/PTC1 |
inv(10)(q11.2q21) |
RET-H4 |
Hyalinizing Trabecular Tumor; Molecular Pathology of Thyroid Neoplasms; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Diffuse Sclerosing Variant; Papillary Thyroid Carcinoma, Follicular Variant |
RET/PTC2 |
t(10;17)(q11.2;q23) |
RET-R1α |
Molecular Pathology of Thyroid Neoplasms |
RET/PTC3 |
inv(10)(q11.2q11.2) |
RET-ele1 |
Molecular Pathology of Thyroid Neoplasms; Papillary Thyroid Carcinoma; Papillary Thyroid Carcinoma, Follicular Variant; Papillary Thyroid Carcinoma, Solid Variant; Papillary Thyroid Carcinoma, Tall Cell Variant |
SDHA |
5p15 |
succinate dehydrogenase complex, subunit A, flavoprotein |
Familial Paraganglioma-Pheochromocytoma; Multiple Endocrine Neoplasia Type 2; Neuronal Cell Tumors, Pituitary Gland; Pheochromocytoma and Extraadrenal Paraganglioma |
SDHAF2 |
11q12.2 |
succinate dehydrogenase complex assembly factor 2 |
Familial Paraganglioma-Pheochromocytoma; Neuronal Cell Tumors, Pituitary Gland; Pheochromocytoma and Extraadrenal Paraganglioma |
SDHB |
1p36.1-p35 |
succinate dehydrogenase complex, subunit B, iron sulfur |
Composite Tumor, Adrenal Glands; Familial Paraganglioma-Pheochromocytoma; Multiple Endocrine Neoplasia Type 2; Neuronal Cell Tumors, Pituitary Gland; Pheochromocytoma and Extraadrenal Paraganglioma |
SDHC |
1q23.3 |
succinate dehydrogenase complex, subunit C, integral membrane protein |
Familial Paraganglioma-Pheochromocytoma; Multiple Endocrine Neoplasia Type 2; Neuronal Cell Tumors, Pituitary Gland; Pheochromocytoma and Extraadrenal Paraganglioma |
SDHD |
11q23 |
succinate dehydrogenase complex, subunit D, integral membrane protein |
Familial Paraganglioma-Pheochromocytoma; Merkel Cell Carcinoma; Multiple Endocrine Neoplasia Type 2; Neuronal Cell Tumors, Pituitary Gland; Pheochromocytoma and Extraadrenal Paraganglioma |
SLC26A4 |
7q31 |
PDS; pendrin |
Adenomatous Nodules; Familial Thyroid Carcinoma; Follicular Adenoma |
SMAD4 |
18q21.1 |
SMAD family member 4; DPC |
Pancreatic Endocrine Neoplasms |
SSTR2 |
17q24 |
somatostatin receptor 2 |
TSH-producing Adenoma |
STK11 |
19p13.3 |
serine/threonine kinase 11; LKB1 |
Carney Complex |
SYT-SSX1 |
t(X;18)(p11;q11) |
|
Leiomyosarcoma, Adrenal Glands |
SYT-SSX2 |
t(X;18)(p11;q11) |
|
Leiomyosarcoma, Adrenal Glands |
t(1;13) |
t(1;13) |
|
Neuroblastoma and Related Tumors |
t(11;22)(q24;q12) |
t(11;22)(q24;q12) |
|
Primary Thyroid Ewing Sarcoma, Thyroid |
t(2;13) |
t(2;13) |
|
Neuroblastoma and Related Tumors |
t(2;3)(q13;p25) |
t(2;3)(q13;p25) |
PAX8-PPARγ |
Follicular Thyroid Carcinoma; Molecular Pathology of Thyroid Neoplasms |
t(X;18) |
t(X;18) |
|
Spindle Cell Tumor with Thymus-like Differentiation |
t(X;18)(p11;q11) |
t(X;18)(p11;q11) |
SYT-SSX |
Spindle Cell Tumor with Thymus-like Differentiation |
TMEM127 |
2q11.2 |
transmembrane protein 127 |
Pheochromocytoma and Extraadrenal Paraganglioma |
TP53 |
17p13.1 |
tumor protein p53 |
Adrenal Cortical Carcinoma; Follicular Thyroid Carcinoma; Merkel Cell Carcinoma; Molecular Pathology of Thyroid Neoplasms; Pancreatic Endocrine Neoplasms; Papillary Thyroid Carcinoma, Follicular Variant; Poorly Differentiated Thyroid Carcinoma; Poorly Differentiated Thyroid Carcinoma; Spindle Cell Tumor with Thymus-like Differentiation; Undifferentiated/Anaplastic Thyroid Carcinoma |
Trisomy 12 |
12 |
|
Prolactin-producing Adenoma |
Trisomy 20 |
20 |
|
Prolactin-producing Adenoma |
Trisomy 5 |
5 |
|
Prolactin-producing Adenoma |
Trisomy 6 |
6 |
|
Merkel Cell Carcinoma |
Trisomy 7 |
7 |
|
Prolactin-producing Adenoma |
Trisomy 8 |
8 |
|
Prolactin-producing Adenoma |
Trisomy 9 |
9 |
|
Prolactin-producing Adenoma |
TRK (see NTRK1) |
|
|
|
TSC1 |
9q34 |
tuberous sclerosis 1 |
Pancreatic Endocrine Neoplasms |
VHL |
3p25.3 |
von Hippel-Lindau tumor suppressor |
Composite Tumor, Adrenal Glands; Familial Paraganglioma-Pheochromocytoma; Multiple Endocrine Neoplasia Type 2; Neuronal Cell Tumors, Pituitary Gland; Pheochromocytoma and Extraadrenal Paraganglioma; von Hippel-Lindau Disease |
WRN |
8p12 |
Werner syndrome, RecQ helicase-like |
Familial Thyroid Carcinoma |
