2 Molecular cell biology and genetic disorders Questions Question 1 As cells grow and regenerate, what mechanism does the body use to get rid of the continuously dying cells? And what kind of cells can’t be replaced once dead? Question 2 I cannot find out why some of the autosomal dominant diseases have a male or female preponderance, e.g. I have never seen a female Marfans. I was attributing it to imprinting but on reading about imprinting in detail it cannot be the case. Question 3 We have been told that some tumours in the colon are associated with microsatellite instability. What does this mean? Question 4 I understand that microarrays are being used to define the molecular abnormality and the prognosis in some patients with leukaemia. What are microarrays? Question 5 Why do mitochondrial diseases cause a myopathy? Question 6 Why do successive generations of patients with some genetic disorders present earlier and with progressively worse symptoms. Question 7 Does a normal serum uric acid level exclude the diagnosis of Lesch-Nyhan syndrome? Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading... Related Related posts: Gastrointestinal disease Liver, biliary tract and pancreatic disease Infectious diseases, tropical medicine and sexually transmitted infection Psychological medicine Stay updated, free articles. Join our Telegram channel Join Tags: 1000 Questions and Answers from Kumar Clarks Clinical Medicine Dec 3, 2016 | Posted by admin in GENERAL & FAMILY MEDICINE | Comments Off on Molecular cell biology and genetic disorders Full access? Get Clinical Tree
2 Molecular cell biology and genetic disorders Questions Question 1 As cells grow and regenerate, what mechanism does the body use to get rid of the continuously dying cells? And what kind of cells can’t be replaced once dead? Question 2 I cannot find out why some of the autosomal dominant diseases have a male or female preponderance, e.g. I have never seen a female Marfans. I was attributing it to imprinting but on reading about imprinting in detail it cannot be the case. Question 3 We have been told that some tumours in the colon are associated with microsatellite instability. What does this mean? Question 4 I understand that microarrays are being used to define the molecular abnormality and the prognosis in some patients with leukaemia. What are microarrays? Question 5 Why do mitochondrial diseases cause a myopathy? Question 6 Why do successive generations of patients with some genetic disorders present earlier and with progressively worse symptoms. Question 7 Does a normal serum uric acid level exclude the diagnosis of Lesch-Nyhan syndrome? Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading... Related Related posts: Gastrointestinal disease Liver, biliary tract and pancreatic disease Infectious diseases, tropical medicine and sexually transmitted infection Psychological medicine Stay updated, free articles. Join our Telegram channel Join Tags: 1000 Questions and Answers from Kumar Clarks Clinical Medicine Dec 3, 2016 | Posted by admin in GENERAL & FAMILY MEDICINE | Comments Off on Molecular cell biology and genetic disorders Full access? Get Clinical Tree
