15 Membrane vesicle transport Questions How does the uptake of particulates and solutes differ? What is the driving force for transport vesicle formation? What is the function of SNAREs in vesicular transport? Phagocytosis and pinocytosis Phagocytosis is the internalization of receptor-bound particulate material by the evagination of psuedopods and a membrane ‘zippering-mechanism’ to engulf the particle for degradation in lysosomes. In mammals, this process is found only in specialized cells (e.g. macrophages and neutrophils). Pinocytosis, leading to the uptake of solutes and retrieval of plasma membrane to balance that inserted by the secretory pathways, occurs by membrane invagination. ‘Fluid-phase’ endocytosis permits the uptake of entrapped solutes, while receptor-mediated endocytosis provides a mechanism for the selective uptake of molecules bound to cell-surface receptors. Most endocytic vesicles ultimately fuse with primary lysosomes to form secondary lysosomes, in which internalized materials are digested. Membrane trafficking Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading... Related Related posts: Kinases and phosphatases in cell signalling Ion pumps and ion exchangers Electrical conduction in nerves Proteins and protein function Stay updated, free articles. Join our Telegram channel Join Tags: The Flesh and Bones of Medical Cell Biology Jun 18, 2016 | Posted by admin in BIOCHEMISTRY | Comments Off on Membrane vesicle transport Full access? Get Clinical Tree
15 Membrane vesicle transport Questions How does the uptake of particulates and solutes differ? What is the driving force for transport vesicle formation? What is the function of SNAREs in vesicular transport? Phagocytosis and pinocytosis Phagocytosis is the internalization of receptor-bound particulate material by the evagination of psuedopods and a membrane ‘zippering-mechanism’ to engulf the particle for degradation in lysosomes. In mammals, this process is found only in specialized cells (e.g. macrophages and neutrophils). Pinocytosis, leading to the uptake of solutes and retrieval of plasma membrane to balance that inserted by the secretory pathways, occurs by membrane invagination. ‘Fluid-phase’ endocytosis permits the uptake of entrapped solutes, while receptor-mediated endocytosis provides a mechanism for the selective uptake of molecules bound to cell-surface receptors. Most endocytic vesicles ultimately fuse with primary lysosomes to form secondary lysosomes, in which internalized materials are digested. Membrane trafficking Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading... Related Related posts: Kinases and phosphatases in cell signalling Ion pumps and ion exchangers Electrical conduction in nerves Proteins and protein function Stay updated, free articles. Join our Telegram channel Join Tags: The Flesh and Bones of Medical Cell Biology Jun 18, 2016 | Posted by admin in BIOCHEMISTRY | Comments Off on Membrane vesicle transport Full access? Get Clinical Tree
