Melanoma In Situ, Lentigo Maligna Type



Melanoma In Situ, Lentigo Maligna Type


Soheil Sam Dadras, MD, PhD










Clinical photograph of a lentigo maligna type of melanoma in situ shows an irregularly shaped and unevenly pigmented image lesion on the scalp of an elderly patient.






Histologic examination of MIS-LMT shows a junctional melanocytic proliferation, which is composed of atypical, hyperchromatic-staining single cells, including several multinucleated tumor cells image.


TERMINOLOGY


Abbreviations



  • Melanoma in situ, lentigo maligna type (MIS-LMT)


Synonyms



  • Hutchinson melanotic freckle


  • Precancerous melanosis of Dubreuilh


Definitions



  • Slowly evolving, indolent melanoma subtype that usually presents on head and neck (sun-exposed regions) in older patients


ETIOLOGY/PATHOGENESIS


Environmental Exposure



  • Long-term exposure to ultraviolet irradiation


CLINICAL ISSUES


Epidemiology

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Melanoma In Situ, Lentigo Maligna Type
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