Lobelia
Lobelia inflata L.
Synonyms:
L. michauxii Nutt; and others
Family:
Campanulaceae
Other common name:
Indian tobacco; puke weed
Drug name:
Lobeliae herba
Botanical drug used:
Herb
Main chemical compounds:
The active constituents are the piperidine alkaloids, mainly lobeline, but also lobelanine, lobelanidine, norlobelanine, lelobanidine, norlelobanidine, norlobelanidine and lobinine (Felpin and Lebreton 2004; Williamson et al. 2013).
Clinical evidence:
No data available to support the traditional use for respiratory tract disorders. A Cochrane review suggests that there is no evidence from long-term trials to show that lobeline can aid smoking cessation, and the short-term evidence also suggests there is no benefit (Stead and Hughes 2012).
Pre-clinical evidence and mechanisms of action:
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