The final section of the book is devoted to the anatomy of the lower extremity as encountered by the general surgeon. First, a discussion of soft tissue infections including necrotizing fasciitis introduces the fascial and fatty layers of the region. Next, a series of chapters on amputations introduce the muscle groups and neurovascular structures. Chapter 127 details techniques for the so-called minor amputations of the digits and forefoot. These are often performed by junior residents, yet meticulous attention to patient selection and technique is imperative for proper healing. This is also true for major amputations—the below-knee amputation (Chapter 128) and the above-knee amputation (Chapter 129). Amputation at other levels, such as the Syme amputation, knee or hip disarticulation, and hemipelvectomy, are detailed in the references.