Chapter 60 Infrainguinal Revascularization
INTRODUCTION
Lower extremity revascularization is being offered to an increasing number of patients. This is due in part to the aging of our population, but the population is also increasingly active and aware of the effects of peripheral arterial disease on lifestyle and mobility. Advances in open and endovascular therapies have allowed an increasingly aggressive approach to revascularization for a patient population that is becoming increasingly older and often sicker. These factors continue to increase the number of prospective patients seeking revascularization to increase mobility and avoid amputation. Although the advent of sophisticated endovascular techniques continues to push the limits of catheter-based revascularization, open bypass will continue to play a major role in the revascularization of the critically ischemic lower extremity. This may prove especially true for those patients who are in need of pulsatile flow directly to a specific angiosome to prevent tissue loss.
The classic indications for revascularization are incapacitating claudication, rest pain, and tissue loss including gangrene and nonhealing ulcerations.1 Patient selection is important in determining the optimal mode of therapy because pain relief and maintenance of function are the goals of revascularization and not the cure of atherosclerosis. Claudication is rarely a limb-threatening situation, and a failed intervention can result in a more complicated revascularization and conversion to the threat of limb loss. Whereas 25% of claudicants have progressive symptoms, fewer than 20% require revascularization for limb salvage after 10 years.2 The majority of infrapopliteal revascularization procedures should be performed for patients in a limb-threatening situation with symptoms manifesting as pain at rest or tissue loss. In these patients, both an aggressive approach to revascularization and proper wound care are essential to maintain limb length and the ambulatory status of the patient. This affects both life and limb.
The noninvasive vascular laboratory uses Doppler ultrasound to measure the ankle/brachial index (ABI), segmental pressures, and waveform analysis and to generate duplex images. Other important tests include pulse volume recordings (PVR), transcutaneous oxygen tension (tcPO2) and photoplethysmography (PPG). The ABI is measured as the ankle pressure divided by the brachial pressure, with a normal value of 1.0. In intermittent claudication, an ABI of 0.5 to 0.9 is usually obtained, whereas in severe ischemia, the ABI is usually less than 0.5. Noncompressible arteries lead to falsely high ankle pressures in more than 30% of diabetic patients3; therefore, other noninvasive studies should be added to determine the adequacy of blood flow in diabetics with ischemia.4 Segmental pressures and waveforms can help localize vascular occlusive disease. The tcPO2 measures the partial pressure of oxygen that diffuses through heated skin.5 A tcPO2 can be accurate in predicting healing. Healing is likely if tcPO2 is above 35 to 40 mm Hg, and unlikely if it is below 20 to 26 mm Hg. A tcPO2 regional index can be used to account for changes in systemic arterial oxygen tension.6 To obtain the regional index, the tcPO2 of the leg is divided by the tcPO2 measured at a reference point (chest). Wounds with a tcPO2 index below 0.4 are unlikely to heal, and those with tcPO2 above 0.6 are likely to heal.7
After it has been determined that revascularization is indicated, an imaging study is needed to plan the appropriate procedure. Arteriography remains the most common method for arterial imaging in order to plan revascularization. However, new modalities such as duplex ultrasound, magnetic resonance angiography, and computed tomographic (CT) angiography are being used with increasing frequency. These new modalities avoid the complications of arterial puncture and possible renal dysfunction associated with arteriography. However, these newer, noninvasive imaging modalities are still being refined and require the involvement of physicians dedicated to obtaining precise images. The chosen method must allow the surgeon to identify the inflow and outflow arteries as well as the adequacy of the runoff—all key factors for a successful bypass.
A successful bypass depends on careful preoperative planning and meticulous attention to detail during the operation. Preoperative decisions include choice of inflow artery, recipient artery, and the conduit for bypass. Error in judgment in any of these decisions is a technical error leading to graft failure. Meticulous dissection, conduit preparation, and suturing of the anastomosis are crucial in preventing intraoperative technical errors leading to early graft failure. There is little margin for error in suturing anastomoses, especially to those small diseased arteries below the knee.
OPERATIVE PROCEDURE
Proximal Artery Exposure
Proximal arterial exposure involves proper choice of the inflow artery for bypass. Several methods exist to aid this choice. Presence of a strong, palpable pulse and preoperative imaging should be considered. Any doubt requires measurement of an arterial pressure, which can be performed at the time of surgery.8 Careful dissection with minimal tissue manipulation and respect for anatomic tissue planes can avoid the complications associated with this portion of the procedure. There is some support for the use of a transverse groin incision as opposed to a vertical incision in order to avoid lymphoceles and seromas (Fig. 60-1). This decision should not compromise appropriate arterial exposure.
Improper Choice of Inflow Artery
• Prevention
Femoral Nerve Injury (Fig. 60-2)
• Consequence
• Prevention
Distal Artery Exposure
Similar principles apply to the distal dissection as to the proximal exposure. Ideally, distal arteries can be dissected between muscle planes and not through a large mass of muscle. If large amounts of muscle are being transected, reconsider the proper plane of dissection (Fig. 60-3).
Venous Injury (Fig. 60-4)
• Consequence

Figure 60-3 A, Incision planning for below-knee popliteal exposure. B, Incision for below-knee popliteal exposure. C, Distal exposure for the dorsalis pedis artery. D, Distal exposure for the plantaris pedis branch of the posterior tibial artery.
• Repair
• Prevention
Common Peroneal Nerve Injury
• Consequence
• Prevention
Superficial Peroneal Nerve Injury
• Prevention
Tibial Nerve Injury
• Prevention
Preparation of Conduit
Preparation of the conduit is obviously most important if autogenous vein is available to use for the bypass. Sources for venous conduit include the greater saphenous, lesser saphenous, and arm veins. If vein is not available, prosthetic materials can be used prior to the choice of primary amputation. However, every effort should be made to use an autogenous reconstruction. In this case, the avoidance of venous spasm and injury demands meticulous dissection and gentle vein handling. This is a crucial part of the operation and not one that should be left to the most junior member of the operating team (Fig. 60-5).
Saphenous Nerve Injury (Fig. 60-6)
• Consequence

Figure 60-5 A, Autogenous vein harvest for bypass conduit. B, Vein harvest shows the vein cannula in place to administer gentle hydrostatic dilation during harvest and a skin bridge for enhancement of wound closure at the knee.
• Prevention
Vein Spasm, Vein Injury, Poor Vein Quality (Fig. 60-7)
• Consequence

Figure 60-7 Duplex ultrasound image of the greater saphenous vein taken preoperatively to assess vein quality and suitability for use as a bypass conduit. A, Transverse view. B, Longitudinal view. This technique can also guide the operative exposure and help avoid larger tissue flaps that result in postoperative wound complications.
• Prevention
Residual Arteriovenous Fistula (Fig. 60-8)
• Consequence
• Prevention
Failure to Lyse All Venous Valves (Fig. 60-9)
• Prevention

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