15 Most adverse reactions to essential oils are without any serious consequence, but if young children ingest any amount, medical attention should be sought urgently. After suspected ingestion of an essential oil, asymptomatic children are normally observed for six hours, and drinking of water is encouraged. Symptomatic children require hospital admission (Riordan et al 2002). Activated charcoal is regarded as ineffective for treating essential oil poisoning (Jepsen & Ryan 2005). A summary of first aid procedures for essential oil toxicity is given in Box 15.1. The advice given to doctors dealing with essential oil poisoning following oral ingestion is that the initial effects generally include mucosal irritation, epigastric pain, vomiting and diarrhea, and that convulsions, CNS depression and hepatic and renal failure may follow (Riordan et al 2002). Table 15.1 gives a summary of common signs and symptoms of poisoning by essential oils. Many published cases of poisoning are detailed in the appropriate essential oil profile in Chapter 13. Table 15.1 Poisoning from specific essential oils after acute oral ingestion In the US, consumers and health professionals can report adverse events from essential oils electronically by visiting the FDA’s Medwatch site at https://www.accessdata.fda.gov/scripts/medwatch/medwatch-online.htm (accessed August 28th 2012). In Canada, essential oil reactions can be reported to Health Canada, by visiting http://www.hc-sc.gc.ca/ahc-asc/media/advisories-avis/reaction-eng.php#Consumer (accessed August 28th 2012). In the UK, the equivalent body is the MHRA, and their website can be accessed at http://www.mhra.gov.uk/index.htm (accessed August 28th 2012). However, there is no provision for reporting reactions to essential oils. In Australia, adverse events can be reported to the Therapeutic Goods Administration http://www.tga.gov.au (accessed August 28th 2012). The following are guidelines for preventing or managing adverse reactions. • do not apply undiluted essential oils to any part of the body • before applying to the skin, essential oils should be appropriately diluted, depending on the oils used • adding undiluted essential oils to bathwater is inadvisable • individuals with a personal or family history of atopic dermatitis, with a history of skin contact allergy or perfume allergy, or with a current skin condition, may be at greater risk of adverse skin reactions.
General safety guidelines
First aid
Signs and symptoms of toxicity
Essential oil
Signs and symptoms
Camphor
Initially CNS stimulation (delirium, convulsions), followed by depression (ataxia, coma)
Possibly nausea, vomiting, vertigo, confusion, respiratory failure
Cinnamon bark
A burning sensation in the mouth, chest and stomach, dizziness, double vision, nausea, vomiting, collapse
Citronella
Vomiting, shock, frothing at the mouth, fever, deep and rapid respiration, cyanosis, convulsions
Clove
Acidosis, deteriorating liver function, CNS depression, deep coma, convulsions, ketonuria, low blood glucose
Eucalyptus
CNS depression (drowsiness, coma), abnormal respiration (shallow or labored breathing), pinpoint pupils, ataxia, vertigo, epigastric pain, vomiting, weakness in the legs, cold sweats, headache
Hyssop
Convulsions
Parsley/apiole
Fever, severe abdominal pain, vaginal bleeding, vomiting, diarrhea
Pennyroyal
Fever, delirium, nausea, vomiting, dizziness, coma, tingling and numbness of the extremities, hemorrhage
Pine
Drowsiness, delirium, headache, nausea, ataxia, tachycardia, paresis, gastroenteritis, toxic nephritis, renal failure
Sage (Dalmatian)
Convulsions
Thuja
Convulsions, gastroenteritis, flatulence, hypotension
Sassafras
Principally shock, vomiting. CNS depression causing inadequacy of respiration and blood circulation. Similar clinical picture to that of eucalyptus, except for pinpoint pupils
Tea tree
Convulsions, ataxia, drowsiness
Wintergreen/methyl salicylate
Convulsions, vomiting, fever, rapid and labored breathing, cyanosis, tachycardia, respiratory alkalosis, tinnitus, deafness
Wormseed
Generalized edema, skin and mucous membrane irritation, headache, vertigo, tinnitus, double vision, nausea, vomiting, constipation, deafness, blindness
Reporting adverse events
Safety in healthcare
Adverse skin reactions
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