Fibroma of Tendon Sheath
David R. Lucas, MD
Key Facts
Terminology
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Small benign fibrous nodule typically attached to tendon sheath
Clinical Issues
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Most common in fingers
Macroscopic Features
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Median size: ≈ 2 cm (range: 0.5-5 cm)
Microscopic Pathology
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Well demarcated
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Attached to tendon or tendon sheath
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Benign fibroblasts and myofibroblasts
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Slit-like vascular spaces
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Cellular nodular fasciitis-like areas
Top Differential Diagnoses
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Nodular fasciitis
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Superficial fibromatosis
Fibroma of tendon sheath (FTS) typically presents as a small soft tissue nodule in a finger. This micrograph depicts a circumscribed fibroma  attached to a synovial-lined tendon sheath  . |
The proliferating cells in FTS are fibroblasts and myofibroblasts characterized by bipolar spindle and stellate cells with abundant amphophilic cytoplasm and vesicular nuclei with solitary nucleoli. |
TERMINOLOGY
Abbreviations
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Fibroma of tendon sheath (FTS)
Definitions
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Small benign fibrous nodule typically attached to tendon sheath
ETIOLOGY/PATHOGENESIS
Histogenesis
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Generally regarded as reactive nonneoplastic process
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Single report of clonal chromosomal aberration t(2:11)
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Possibly neoplastic process
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CLINICAL ISSUES
Epidemiology
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Incidence
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Uncommon, exact incidence unknown
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Age
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