F
Fx, Fy, Fz symbols denoting resolved components of ground reaction force (anteroposterior, vertical and horizontal components respectively); Figure F1
facet smooth area on bone denoting articulation with adjacent bone, tendon, ligament or bursa
facies characteristic facial appearance associated with a particular condition
false negative; FN inaccurate investigative or diagnostic test response, giving a ‘no’ response where the correct response should be ‘yes’, so that potentially pathological conditions are missed (see false positive)
false plantar fascia bow strapping
false positive; FP inaccurate investigative or diagnostic test response, giving a ‘yes’ response, where the correct response should be ‘no’; pathological conditions are misdiagnosed as being present (see sensitivity; specificity)
familial feature affecting several close family members
familial dysautonomia see syndrome, Riley–Day
fan strapping soft splintage applied to immobilize a painful first metatarsophalangeal joint (1 MTPJ); longitudinal application of 2.5-cm-wide strips of non-extensible strapping across 1 MTPJ (each strap overlying its neighbour by 50% at medial side of the hallux just proximal to interphalangeal joint, and fanning out as they cross the medial aspect of the 1 MTPJ, so that straps lie adjacent to one another at the midpoint of the shaft of the first metatarsal); see Table S13
fascial groove accommodation see Table O4
fasciculi cuneatus and gracilis nerve fibre tracts with spinal cord dorsal columns
fasciitis inflammation of fascia
fasciotomy incision to divide fascia
fast pain see physiological pain
fasting blood glucose; FBG blood glucose level following fasting, i.e. > 14 hours without food; two consecutive FBG recordings of > 6.7 mmol/L is diagnostic of diabetes mellitus (note: some authorities consider that the cut-off point diagnostic of hyperglycaemia is 5.9 mmol/L); see random blood glucose
fatigue fracture see fracture, fatigue; Table C18
fatty acid any long-chain monobasic organic acid derived from hydrolysis of fats
feedback regulatory mechanisms in which the outcome of system activity governs the amount of further output from the system; e.g. modulation of motor activity by sensory stimuli triggered by muscle contractions
felt wool, or wool/synthetic mix of various thicknesses (2, 5, 7 mm) and compressive qualities (semicompressed, compressed) spread with adhesive mass; shaped and applied to the foot as clinical padding (or fixed to a temporary insole) to realign non-fixed joint deformity, deflect pressure from painful areas, realign areas within the foot, and act as a carrier of medicaments (see Table P2)
feminization acquisition of female characteristics by the male
ferric chloride solution, weak (mitis) 15% ferric chloride solution; may be applied topically to precipitate plasma proteins and aid control of minor skin haemorrhage (see Table A19)
ferritin water-soluble iron–protein complex, used in haemoglobin formation
ferroproteins complex iron-containing proteins, e.g. haem
festinant gait tottering gait, with short, rapid accelerating steps; typical of Parkinson’s disease (see Table G1)
fetal (foetal) origins hypothesis Table F1
Risk factor | Feature of the risk factor |
---|---|
Modifiable factors | |
Smoking | Cigarette smoking is the most powerful risk factor for the development of PAD. It is dose-dependent and the risk declines within 6 months of quitting. A non-smoker is 10 times less likely to develop PAD than a smoker |
Blood lipid disorders | Plasma cholesterol levels of >5.2 mmol/L Increased plasma concentrations of low-density lipoprotein (LDL) cholesterol, low plasma concentrations of high-density lipoproteins (HDLs), and higher concentrations of plasma triglycerides all correlate with increased incidence of PAD Familial hypercholesterolaemia (affecting 1:500 in UK) Familial combined hyperlipidaemia (affecting 1:250 in UK) |
Diabetes mellitus (DM) | Type 2 DM increases risk of PAD by 1.5–4.0, due to the associated hypertension, hyperlipidaemia and altered vascular reactivity |
Hypertension | Raised systolic blood pressure (BP) increases the risk of PAD and atherosclerosis by 4 due to endothelial injury caused by increased intra-arterial shear stresses at the blood–endothelium interface (raised systolic pressures are more predictive than raised diastolic pressures) |
Obesity | Central obesity is an independent risk for PAD, but also predisposes to other risk factors for PAD, such as type 2 DM, hypertension |
Homocysteine | Homocysteine is an amino acid that in high levels is associated with thromboembolism |
Haemostatic variables | Increased levels of clotting factors VII, VIIIC and fibrinogen are associated with increased risk of atherosclerosis |
Sedentary lifestyle | Low levels of regular activity are associated with increased risk of PAD (higher levels of activity are associated with higher levels of plasma HDL-cholesterol and reduced blood pressures and facilitate the development of the collateral circulation) |
Dietary deficiencies | Low levels of antioxidant vitamins (vitamins C and E) and polyunsaturated fatty acids facilitate the formation of oxidized LDLs and thus predispose to the risk of PAD |
Type A behaviours (TABs) | People who tend to aggression, ambitiousness, restlessness, time urgency and high anxiety tend to an increased incidence of PAD, possibly due to increased levels of circulating catecholamines |
Non-modifiable or fixed factors | |
Age and sex | Atherosclerosis is more common in males, and in postmenopausal women |
Family history | Atherosclerosis shows familial patterns of incidence, possibly due to genetic factors and/or lifestyle choices and patterns |
Early environment | Fetal origins hypothesis: adverse conditions in utero or infancy predispose to the risk of cardiovascular disease in later life (e.g. statistically, small-birth-weight babies have a higher incidence in adult life of hypertension, type 2 DM, altered plasma lipids, altered bone densities, altered stress responses, less elastic arteries, thicker-walled ventricles and ‘age’ quicker) |
fetus; foetus product of conception, from 8th week of intrauterine life until point of birth
fever pyrexia: body temperature >37°C (>98.4°F)
fibre nerve cell axon and its glial envelope
fibrinolysis hydrolysis of fibrin; i.e. initiation of blood clot dissolution
fibroadenoma benign neoplasm derived from glandular epithelium
fibrocartilage cartilage with prominent collagen fibrils
fibroelastic composed of collagen and elastic fibres
fibroma benign neoplasm derived from fibrous connective tissue
fibromatosis formation of multiple widespread fibromas
fibromyositis chronic inflammation of a muscle with associated overgrowth of local fibrous connective tissue
fibrosarcoma malignant neoplasm derived from fibrous connective tissue
fibrous corn long-standing hyperkeratotic skin lesion formed within skin areas subject to chronic high loading; characterized by fibrosis of underlying soft tissues, and tying down of superficial tissues to deeper structures (see Table C14)
fibrous histiocytoma see dermatofibroma
fibrous tumours in skin Table F2
Tumour type | Degree of malignancy | Examples |
---|---|---|
Epidermal tumours (see Table E3) | Benign Premalignant Malignant | Seborrhoeic keratoses Bowen’s disease Basal cell carcinoma Squamous cell carcinoma |
Pigmented skin lesions | Benign | Freckle Lentigo |
Pigmented and potentially metastatic skin tumours | Benign | Congenital naevus Acquired naevus Speckled/lentiginous naevus Becker’s naevus Spitz naevus |
Premalignant | Dysplastic naevus Melanoma | |
Malignant | Subungual melanoma | |
Vascular tumours | Benign | Pyogenic granuloma Glomus tumour |
Malignant | Kaposi’s sarcoma | |
Fibrous tumours | Benign | Acquired fibrokeratoma Dermatofibroma |
Malignant | Dermatofibrosarcoma | |
Adnexal tumours | Benign | Eccrine poroma |
Others | Benign | Leiomyoma (smooth muscle) Subungual exostosis (bone) Myxoid cyst (joint lining herniation) Ganglion (joint fluid) Bursitis (joint inflammation) Piezogenic pedal papule (fat herniation) Neurofibromatosis (nerve) |
fibula most lateral of the two bones of lower leg: articulates proximally with inferior aspect of lateral condyle of tibia; distal end forms the lateral malleolus and articulates with lateral aspect of the trochlea of talus; linked throughout its length to lateral border of tibia by an interosseous ligament (see Table O5)
fibular relating to fibula (lateral) side of lower leg or foot
fibular nerve see superficial peroneal nerve
field block; regional block see anaesthesia, field block
figure-of-eight bandage crêpe bandage or strapping applied under mild tension to tarsus and ankle to (1) stabilize rearfoot complex (control inversion/eversion); (2) invert calcaneum (reduce midstance pronation and minimize tension on plantar fascia in plantar fasciitis); (3) evert calcaneum (reduce lateral ankle tension in lateral ankle sprain)
filariasis presence of filarian worms in body tissues; dead worms promote chronic granulomatous inflammation and permanent woody fibrosis, obstruction of local lymphatic vessels, dense subcutaneous scar formation and severe limb oedema (see elephantiasis; kerato pachyderma)
filler pad see tarsal platform
filtrate liquid that has passed through a filter; the filtrate retains any suspended solids
finger clubbing see clubbing of the digits
fingerprint see dermatoglyphics
‘fireside tartan’ see erythema ab igne
first-degree nerve injury see Table N3
first metatarsophalangeal joint; 1 MTPJ synovial joint at the articulation of the base of proximal phalanx, head of first metatarsal, plantar aspect of head of first metatarsal and hallucal sesamoids (embedded within tendon of flexor hallucis brevis muscle); ginglymoarthrodial joint allowing both sagittal-plane hinge movement (dorsiflexion/plantarflexion) of hallux toward the dorsum of first metatarsal head, and gliding sagittal-plane movement as first metatarsal head moves through an arc in a plantarwards direction; combined ginglymoarthrodial 1 MTPJ movement ensures that, immediately before toe off, the pulp of the hallux is in ground contact and the first metatarsal is at almost 90° to the horizontal plane (see Table N6)
first pain see physiological pain
first ray column of bones and associated joints forming medial border of forefoot; i.e. medial cuneiform, first metatarsal, hallucal sesamoids, proximal and distal phalanges of hallux (see Table A6)
first-ray block see anaesthesia, first-rag block
fistula abnormal opening or canal between a hollow organ and the body surface
fixation stabilization of bone following surgery or fracture
fixator muscle/muscle group, contraction of which stabilizes the origin of another muscle
flap mass or tongue of tissue, vascularized by a pedicel (stem)
flare diffuse skin redness, due to vasomotor reaction; characteristic of inflammation or infection
flared heel see buttressed heel
‘fleck’ fracture see fracture, avulsion
flexor a muscle bringing about joint flexion
flexor accessorius; quadratus plantae third-layer intrinsic foot muscle