Elastofibroma



Elastofibroma


Cyril Fisher, MD, DSc, FRCPath









Gross photograph shows a firm white tumor with irregularly infiltrating fat. This formed a firm plaque in the subscapular region; the plaque had been present and slowly enlarging for several years.






Elastic van Gieson shows elastic fibers at high magnification. Note the “string of beads” appearance with aggregated or separated, variably sized, rounded fragments of black-staining elastic material.


TERMINOLOGY


Synonyms



  • Elastofibroma dorsi


Definitions



  • Pseudotumor composed of fragmented abnormal elastic fibers in collagenous stroma


ETIOLOGY/PATHOGENESIS


Environmental Exposure



  • Some related to trauma or friction



    • Some cases reported in manual workers doing repetitive physical labor


    • Similar microscopic changes are found in 15% of autopsies of older patients


Genetic Predisposition



  • Some cases familial


  • Examples occur in visceral locations


  • Possibly formation of abnormal elastic fibers


CLINICAL ISSUES


Epidemiology

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Elastofibroma
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