133 Ehlers–Danlos syndrome
Salient features
History
• Family history (JAMA 1997;278:1284–5)
• Hypermobile joints (Fig. 133.1)
• Fragile skin with impaired wound healing
Examination
Skin
• The skin over the neck, axillae and groin is smooth and elastic (Fig. 133.2). It can be stretched and, when released, it returns immediately to its normal position. Late in the disease it becomes lax, wrinkled and hangs in folds.
Diagnosis
This patient has hypermobile joints (lesion) caused by Ehlers–Danlos syndrome (aetiology).