Dose = 1.75 mg/kg × 106.4 kg × 4 hours = 744.8 mg

5. 1250 mg/m² po bid × 2 weeks, 1 week off then repeat for 3 cycles. BSA = 1.99 m²

Answer

BSA = 1.99 m² (which is approximately 2)

1250 mg/m² × 2 = 2500 mg bid for 2 weeks; off 1 week; repeat for 3 cycles

6. 3 mcg/kg q week × 2, then 5 mcg/kg q2weeks. Patient weight 40 kg

Answer

40 kg × 3 mcg/kg = 120 mcg ea wk for 2 weeks; then

40 kg × 5 mcg = 200 mcg/kg ea wk for 2 more weeks

7. 180 mcg/kg IV bolus followed by 2 mcg/kg/min infusion and a second 180 mcg/kg IV bolus 10 minutes after the first bolus. Patient weight 55 kg

Answer

180 mcg/kg × 55 kg = 9900 mcg IV bolus followed by

2 mcg/kg/min infusion = 2 mcg × 55 kg = 110 mcg/min infusion (1100 mcg infusion total over 10 minutes); then

a second bolus of 9900 mcg 10 minutes later