Digital Mucous Cyst
Senait W. Dyson, MD
David Cassarino, MD, PhD
Key Facts
Terminology
Solitary, dome-shaped, skin-colored to translucent papule
Synonyms: Digital myxoid cyst, digital synovial cyst
Etiology/Pathogenesis
Most view digital mucous cyst and digital myxoid cyst to be synonymous
Microscopic Pathology
Subepidermal cystic space or clefts with collection of mucin and stellate fibroblasts
No epithelial lining
Mucin is positive with colloidal iron and Alcian blue stains
Top Differential Diagnoses
Ganglion cyst
Focal mucinosis
 Earlier lesions show pools of mucin infiltrating between collagen bundles  . Prominent effacement of the overlying epidermal rete ridges is present  . |
 Within a mucinous matrix, an increased number of small vessels  and stromal fibroblasts  are seen. |
TERMINOLOGY
Abbreviations
Digital mucous cyst (DMC)
Synonyms
Digital myxoid cyst
Digital myxoid pseudocyst
Digital synovial cyst
Nail cysts
Periungual ganglions
Myxomatous degenerative cysts
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