Diabetes



DIABETES


In 2012, the total healthcare costs for diagnosed diabetes in the U.S. reached $245 billion.53 In the lead editorial of the July 2013 issue of the American Journal of Medicine, Dr. Joseph S. Alpert, its editor-in-chief and a professor of medicine at the University of Arizona, posed the question: “Is it possible that THC will be commonly prescribed in the future for patients with diabetes or metabolic syndrome . . . ?”54 Alpert’s editorial accompanied a new epidemiological study by University of Nebraska researchers, which indicated that current cannabis users had significantly healthier levels of insulin, as well as less insulin resistance than nonusers of cannabis.


Healthy levels of insulin and insulin resistance translate into fewer instances of diabetes.58 Diabetes and prediabetes affect over 100 million Americans, according to the Centers for Disease Control and Prevention.59 Cannabis and cannabinoid medicines might eventually provide new treatments and prevention approaches for diabetes and related metabolic syndromes.



Historical Uses


In 2000, Raphael Mechoulam (codiscoverer of THC) joined a group of Israeli immunologists to explore the use of cannabinoids as potential treatments for autoimmune disorders such as rheumatoid arthritis.55 Preliminary success in their explorations encouraged the team to examine cannabinoid effectiveness in suppressing or modulating the immune response in the onset and progression of type 1 diabetes in a mouse model.56 Since 2006, research studies have been conducted to determine how cannabinoids might be used to treat diabetes.57 In the United Kingdom, GW Pharmaceuticals is conducting Phase 1 clinical trials with the cannabinoids THCV and CBD to treat fatty liver disease and high cholesterol in type 2 diabetes patients.

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Jun 24, 2016 | Posted by in PHARMACY | Comments Off on Diabetes

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