Desmoplastic Fibroblastoma



Desmoplastic Fibroblastoma


Khin Thway, BSc, MBBS, FRCPath









Hematoxylin & eosin shows desmoplastic fibroblastoma. The lesion is a well-circumscribed ovoid or fusiform mass. The hypocellularity is apparent at low power.






Hematoxylin & eosin shows desmoplastic fibroblastoma. Although most tumors are subcutaneous, some involve skeletal muscle image, which this lesion is seen to abut.


TERMINOLOGY


Abbreviations



  • Desmoplastic fibroblastoma (DF)


Synonyms



  • Collagenous fibroma


Definitions



  • Rare benign fibrous soft tissue neoplasm occurring mainly in adult males and consisting of paucicellular arrays of stellate and spindle fibroblasts


  • Reciprocal translocation t(2;11)(q31;q12) found in some cases


ETIOLOGY/PATHOGENESIS


Developmental Anomaly



  • Etiology unknown


CLINICAL ISSUES


Epidemiology



  • Age



    • All ages, but particularly older adults (5th-6th decades)


  • Gender



    • M > F

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Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Desmoplastic Fibroblastoma

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