T. sativum (Schreb.) Crome ex Boenn; and others Fabaceae (Leguminosae) Cow clover; creeping clover; meadow clover; peavine clover; purple clover; trefoil Trifolii rubri flos; Trifolii pratensis herba Dried inflorescence; aerial parts Isoflavones, the major compound being biochanin A (together with afrormosin, daidzein, formononetin, genistein, orobol, pratensein, trifoside and others), and their glycoside conjugates. Other constituents include coumestrol, medicagol and coumarin, clovamides, soyasaponins, flavonoids and others (Sabudak and Guler 2009; Kolodziejczyk-Czepas 2012). A systematic review was carried out in 2007 to assess the efficacy of supplements containing red clover isoflavones in the reduction of hot flush frequency in menopausal women. The review concluded that there is a marginally significant effect for treating hot flushes in menopausal women. Seventeen potentially relevant articles were retrieved for further evaluation, but only five were suitable for inclusion in the meta-analysis, which indicated a reduction in hot flush frequency in the active treatment group (40–82 mg daily) compared with the placebo group (Coon et al. 2007).
Red Clover
Trifolium pratense L.
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