Pathophysiology
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Colon cancer
Mass causes mechanical LBO
History of weight loss, change in bowel habits, bloody stools
Volvulus (sigmoid or cecal)
Twisting of colon causes mechanical LBO
Sigmoid in elderly patients, debilitated or institutionalized patients with chronic constipation
Diverticulitis (acute or chronic)
Severe bowel wall edema may lead to LBO
Acute diverticulitis: pain and tenderness in LLQ
Stricture
Inflammation and scarring cause colonic narrowing
IBD, chronic diverticulitis, malignancy, abdominal/pelvic radiation; endoscopy can help identify cause
Fecal impaction
Inspissated stool in rectum or sigmoid causes mechanical LBO
Firm stool in rectal vault on exam
Ogilvie’s syndrome (pseudo-obstruction)
Marked colonic distention without mechanical cause can lead to perforation
Debilitated, hospitalized patients, electrolyte imbalances, may decompress with neostigmine or colonoscopy
Small bowel obstruction (SBO)
Most common cause is adhesions in the USA, hernias worldwide
Nausea, extensive vomiting, abdominal surgical scar, hernia bulge
Toxic megacolon
Transmural inflammation of a markedly dilated colon, associated with ulcerative colitis, pseudomembranous colitis, other bacterial colitis
High fever, tachycardia, abdominal tenderness, acidosis, leukocytosis
What Is the Most Likely Diagnosis?
The massive, slowly progressive abdominal distention, combined with obstipation, and X-ray findings are consistent with a large bowel obstruction. The radiologic appearance is most consistent with a sigmoid volvulus.
History and Physical
What Is the Difference Between Obstipation and Constipation?
Constipation implies infrequent stools (<3 per week), usually associated with hard stools. Obstipation implies a complete absence of gas or stool per rectum, which is highly suggestive of a bowel obstruction.
What Are the Classic Physical Exam Findings in Bowel Obstruction?
On physical exam, note the vitals (particularly the presence of fever or tachycardia > 100/min which in association with an intestinal obstruction suggest strangulation with bowel ischemia or perforation). Tachypnea is common with LBO as diaphragm excursion is impaired. On abdominal exam, check for irreducible hernias (leading cause of SBO worldwide). In uncomplicated bowel obstruction, tenderness is generally lacking. The abdomen may be distended and tympanitic. A rectal exam must be performed to rule out fecal impaction, rectal neoplasm, or stricture.
What Clues on History and Physical Examination Help Distinguish Between a SBO and LBO?
SBOs tend to be associated with more pronounced vomiting. In an early SBO, bowel sounds are hyperactive, with “rushes and tinkles” (high-pitched sounds of hyperperistaltic small bowel). Large bowel obstruction is more likely to be associated with more pronounced distention, less or late onset vomiting, and decreased bowel sounds.
Why Is a History of Neurologic or Psychiatric Disorders Important?
Drugs used to treat neurologic (such as Parkinson’s) or psychiatric diseases can affect colonic motility and predispose to chronic constipation, elongation of the sigmoid, and volvulus, as well as colonic pseudo-obstruction.
What Is the Classic Presentation for Ogilvie’s Syndrome?
The patient presents with progressive massive abdominal distention over several days, nausea, and vomiting (similar to an LBO). However, unlike LBO, the classic setting is in someone who is already hospitalized and often in the postoperative setting.
What Are the 5 F’s of Abdominal Distention?
These are the five common causes of abdominal distention: fat (obesity), feces (fecal impaction), fetus (pregnancy), flatus (ileus or obstruction), and fluid (ascites). Flatus and fluid can be distinguished by whether the abdomen is tympanitic (gas) or dull (fluid) to percussion.
Etiology/Pathophysiology
What Are the Most Common Causes of LBO?
In the USA, malignancies (primarily colon cancer) are the most common cause of LBO (more than half of cases), followed by diverticulitis (either acute or chronic with a stricture) and then volvulus.
Where in the Colon Is a Cancer Most Likely to Cause an LBO?
Left-sided colon (smaller diameter) cancers are more likely to cause LBO, whereas right-sided colon cancers are more likely to present with iron deficiency anemia.
What Is the Difference Between Malrotation and Volvulus?
Malrotation is a congenital condition in which the bowel does not reside in its normal anatomic position. As a result, the bowel and its mesentery are not properly fixed/attached and are therefore prone to twisting and becoming obstructed. Provided the bowel and its mesentery do not twist, the malrotation remains asymptomatic. Volvulus is the term used to describe the twisting of the bowel. Volvulus can be a manifestation of malrotation. If the small bowel twists, the term used is midgut volvulus. Volvulus can also occur in the absence of malrotation (i.e., sigmoid volvulus).