Preinvasive Glandular Lesions and Early Invasive Adenocarcinomas Adenocarcinoma in situ Clinical features ■ Adenocarcinoma in situ (AIS), like its invasive counterpart, has increased in incidence over the past 30 years….

Small Cell Carcinoma of Hypercalcemic Type Clinical features ▪ This tumor (SCCH) is the most common undifferentiated ovarian carcinoma in women <40 years of age. The age range has been…

Follicular Lesions Follicle Cyst Clinical features ■ Solitary follicle cysts (FCs) are most common in nonpregnant women of reproductive age, particularly around the menarche and menopause and are likely due…

Trophoblastic Lesions ■ The WHO classification of gestational trophoblastic disease (GTD) and the TNM and FIGO classifications of gestational trophoblastic tumors are presented in Tables 10.1–10.4 . Table 10.1 Types…

▪ Various non-neoplastic endometrial lesions, as well as normal and artifactual findings, can be problematic for the pathologist, especially their distinction from precancerous endometrial lesions and carcinomas. ▪ Table 7.1…

Precursors Classification ▪ The classifications used for precursors of cervical invasive squamous cell carcinoma (ISqCC), in order of their historical development, are: (1) dysplasia/carcinoma in situ (CIS); (2) cervical intraepithelial…

Tumor-Like Lesions Metaplasias and Ectopias Squamous Metaplasia ( Figs. 4.1 – 4.2 ) ■ This normal process within the transitional zone of postpubertal women results in the replacement of endocervical…

Tumor-Like and Inflammatory Lesions Condyloma Acuminatum ▪ These resemble their vulvar counterparts ( Chapter 1 ) except for a more frequent occurrence of flat condylomas and those with a ‘spiked’…

Viral Infections Human Papillomavirus (Hpv) (Including Condyloma Acuminatum) Clinical and gross features ( Fig. 1.1 ) ▪ Sexually transmitted HPV (usually low-risk types, especially HPV 6 and 11) is the…