- E
See BNF, Appendix 1. This patient should not receive trimethoprim because it is an antifolate and will interact with methotrexate
- B
See BNF, Chapter 10 (Musculoskeletal and joint diseases), section 10.1.3. Folic acid should be given on any day that is different from the methotrexate dose
- B
See BNF, Chapter 2 (Cardiovascular system), section 2.2.1. Thiazide diuretics can cause hyperglycaemia
- C
See MEP 38 and GPhC CPD standards. You can submit your CPD by paper or mixed formats, as long as it complies with the standards for good CPD recording
- B
See BNF, Chapter 10 (Musculoskeletal and joint diseases), section 10.1.1. Naproxen is an NSAID with a significant risk of gastrointestinal side-effects
- B
See BNF, Appendix 1. Important interaction between clopidogrel with omeprazole and esomeprazole, leading to reduced effectiveness of clopidogrel
- E
See MEP 38, section 3.3.10.2. Full packs can be supplied, thus a full calendar pack should be supplied
- E
See BNF, Chapter 4 (Central nervous system), section 4.6, Drugs used in nausea and vertigo, Vomiting in pregnancy. This patient is in the first trimester, so her nausea should be self-limiting and drug treatment is not necessary
- E
See BNF, Chapter 6 (Endocrine system), section 6.2.2, Antithyroid drugs, Neutropenia and agranulocytosis. This patient needs to be referred to her GP for further investigations
- E
See MEP 38, section 3.2.5. Children under 6 years of age should be given simple cough syrups, or encouraged to drink plenty of fluids
- C
See BNF, Chapter 3 (Respiratory system), section 3.4.1. Chlorphenamine is the only sedating antihistamine, which would not be suitable for a security guard
- C
See BNF, Chapter 10 (Musculoskeletal and joint diseases), section 10.1.1. NSAIDs increase the risk of gastrointestinal bleeding, as does hepatic impairment and increased alcohol intake
- A
See BNFC, Chapter 2 (Cardiovascular system), section 2.9. Aspirin associated with development of Reye’s syndrome in children.
See BNFC, Chapter 10 (Musculoskeletal and joint diseases), section 10.1.1. The other listed drugs may be used to treat postsurgical pain in children
- E
See MEP 38, Appendix 6 and GPhC guidance on raising concerns. You should report concerns to your line manager, and/or the line manager of the pharmacist you have a concern about, before reporting it to the GPhC
- C
See BNF, Chapter 2 (Cardiovascular system), section 2.1.1, Cardiac glycosides, Digoxin, side-effects
- B
See BNF, Chapter 2 (Cardiovascular system), section 2.1.1. Hypokalaemia may precipitate digoxin toxicity
- D
See BNF, Chapter 10 (Musculoskeletal and joint diseases), section 10.1.1. Pupil dilation is not a listed side-effect of NSAIDs
- D
See NICE Clinical Guidance 91. Cognitive Behavioural Therapy, and similar individual or group therapies, are listed as first-line options for patients with newly diagnosed depression and a long-term condition
- E
See MEP 38, section 3.6. Because this product is licensed for use in this disease in this species, it is not necessary to follow the veterinary prescribing cascade
- B
See MEP 38, section 3.7.11. CD registers must be retained for at least 2 years after the last entry is made
- A
See BNF, Appendix 3 and Chapter 2 (Cardiovascular system), section 2.3.2. Amiodarone can cause phototoxic reactions
- B
See British Pharmacopoeia, Appendix XVIII. Filtration used when the methods of terminal sterilisation cannot be used
- E
See MEP 38, section 2.9 and GPhC standards for CPD. Pharmacists are encouraged to use multiple, and varied methods to undertake CPD
- D
See BNFC, Chapter 9 (Nutrition and blood), section 9.2.1.2, Oral rehydration therapy. Antimotility drugs not recommended in children under 12 years of age
- A
See MEP 38, section 3.7.7. Temazepam prescriptions are only valid for 28 days (4 weeks)
- D
See MEP 38, section 3.7.7. Once daily is a frequency but does not state a dose, i.e. how many tablets to take
- A
See MEP 38, section 3.7.2. Repeats are not allowed for schedules 2 and 3; instalment prescriptions are required
- B
See BNF, Chapter 5 (Infections), section 5.1. Table 1 states that clarithromycin can be used in those with penicillin allergy. Note the presence of beta-lactam rings in cephalosporin and carbapenem structures
- D
See NICE Clinical Guidance 127. ACE inhibitors are a first-line therapy in Caucasian patients under the age of 55. Low-cost angiotensin receptor blockers may be used as a first-line therapy but candesartan is not available as a generic drug, unlike losartan or valsartan
- D
See BNF, Chapter 2 (Cardiovascular system), section 2.5.5.1. ACE inhibitors may cause profound first-dose hypotension so the patient should take the first dose at bedtime to avoid falls
- B
See BNF, Chapter 2 (Cardiovascular system), section 2.5.5.1. ACE inhibitors can cause persistent dry cough, which can affect sleep
- D
See BNF, Chapter 2 (Cardiovascular system), section 2.12. Atorvastatin is a longer-acting statin so may be taken at any time of day. Compare the dosing instructions in monographs for simvastatin and atorvastatin
- E
Patients suffering diarrhoea after returning from travel abroad should be advised to see their GP for further investigations
- A
See RPS support documents on Medicines Optimisation
- A
See BNF, Chapter 2 (Cardiovascular system), section 2.2.3. Amiloride is the only potassium-sparing diuretic listed
- B
See BNF, Chapter 2 (Cardiovascular system), section 2.2.2. Furosemide can be given twice a day but its duration of action is 6 hours. Therefore, it should not usually be given any later than 4 pm
- C
See BNF, Chapter 2 (Cardiovascular system), section 2.2.1. Thiazide diuretics may precipitate gout
- D
See MEP 38, section 3.7.11. Keeping a running balance is best practice, and not a legal requirement
- B
Martindale: The Complete Drug Reference contains international brand names
- A
See MEP 38, section 3.6. The address of the prescriber is not needed, only their name
- C
Fridge temperatures can range between 2°C and 8°C
- C
See BNF, Chapter 4 (Central nervous system), section 4.2.3, Drugs used for mania and hypomania, Lithium, serum concentrations. See list of overdose signs and symptoms
- D
See NICE Clinical Guidance 66 and 87. Metformin is first-line therapy for both normal weight and overweight patients
- B
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