Brazilian paw paw; corossol; guanábana; prickly custard apple
No authorised botanical drug products are available. Marketed on the Internet as ‘Triamazon’ or graviola
Leaves, seeds and bark. The fruit is eaten widely in the tropics and used to produce beverages.
Indications/uses: An extract is being advocated for treatment of cancer, mainly on the Internet. Traditionally, the leaves are taken as a herbal tea for a wide variety of illnesses, including cancer, hypertension, diabetes, fever, indigestion, nervousness, palpitations and skin diseases. It is also applied externally to kill ectoparasites.
Evidence: There is experimental evidence supporting many of the traditional uses, and selective cytotoxicity has been observed in vitro in various cancer lines. There is no clinical evidence available.
Safety: The fruit pulp is considered safe (see below) but there are concerns over the use of the leaf, seeds and bark.
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