Ampullary Adenoma



Ampullary Adenoma


Mari Mino-Kenudson, MD









A single circumscribed mass with a nodular surface occupies the ampulla. The histology of this lesion showed a tubulopapillary adenoma with invasive adenocarcinoma.






This ampullary papillary adenoma focally extends into the distal common bile duct epithelium image.


TERMINOLOGY


Definitions



  • Intestinal-type adenoma of ampullary or periampullary region



    • Resembles adenomas of small and large bowel


CLINICAL ISSUES


Epidemiology



  • Incidence



    • 55% of small intestinal adenomas



      • Most are sporadic


    • Seen in 50-95% of patients with familial adenomatous polyposis (FAP) and Gardner syndrome



      • Most common site of extracolonic polyps in FAP patients


  • Age



    • Range: 30-80 years



      • Average: 60s


    • Polyposis syndrome patients develop them at younger age


  • Gender



    • M:F ratio = 1:2.6 in sporadic setting


    • No gender predominance in polyposis syndromes

Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Ampullary Adenoma
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