Acinar Cell Cystadenoma
Vikram Deshpande, MD
Key Facts
Terminology
-
Benign pancreatic cyst lined by acinar cells
Clinical Issues
-
Young to middle-aged
-
Benign cyst without risk of malignant transformation
Macroscopic Features
-
Unilocular to multilocular thin-walled cyst(s) filled with serous fluid
Microscopic Pathology
-
Cysts lined by single layer of cuboidal epithelium without multilayering
-
Budding/incipient acinar structures frequently seen, providing evidence of acinar differentiation
Ancillary Tests
-
Lining cells are positive for trypsin &/or lipase
TERMINOLOGY
Definitions
-
Benign pancreatic cyst lined by cells with acinar cell differentiation
CLINICAL ISSUES
Epidemiology
-
Age
-
Young to middle-aged
-
Reported range: 16-66 years
-
-
Gender
-
More common in women
-
Presentation
-
Abdominal pain
-
Incidentally detected by imaging
Natural History
-
Benign cyst without risk of malignant transformation
Treatment
-
Surgical resection is curative
Prognosis
-
Benign tumor with excellent prognosis
IMAGE FINDINGS
General Features

Stay updated, free articles. Join our Telegram channel

Full access? Get Clinical Tree

