Classification of Cystic Diseases
Classification of Cystic Diseases Helen Liapis, MD Joseph Gaut, MD, PhD Adult ADPKD kidneys are massively enlarged and contain numerous oval/spherical cysts dispersed throughout the cortex and medulla. Cysts are…
Blastomycosis
Blastomycosis Anthony Chang, MD Key Facts Etiology/Pathogenesis Blastomyces dermatitidis Endemic to central/southern United States, Canada Reported in Central/South America, Europe, and Africa Ubiquitous dimorphic fungus acquired by inhalation Macroscopic Features…
Lead and Other Heavy Metal Toxins
Lead and Other Heavy Metal Toxins Shane M. Meehan, MBBCh Key Facts Terminology Renal disease due to toxic effects of lead and other metals Etiology/Pathogenesis Principal toxic metals encountered include…
Tubulointerstitial Nephritis with Uveitis
Tubulointerstitial Nephritis with Uveitis A. Brad Farris, III, MD Key Facts Terminology Tubulointerstitial nephritis with uveitis (TINU) Etiology/Pathogenesis Autoimmune, infectious, environmental, and genetic Most likely cause in most cases is…
Renal Lymphangiectasis
Renal Lymphangiectasis Aleksandr Vasilyev, MD, PhD Key Facts Terminology Hamartomatous or acquired obstructive lesion resulting in cystic dilatation of kidney lymphatics Clinical Issues No age or gender predilection; may be…
Ureter: Margins
Ureter: Margins A small length of ureter received for frozen section should be oriented and embedded in such a way that a complete cross section of the lumen is obtained….
Uric Acid Nephropathy/Gout
Uric Acid Nephropathy/Gout Shane M. Meehan, MBBCh Key Facts Terminology Intrarenal precipitation of uric acid associated with hyperuricemia Etiology/Pathogenesis Decreased uric acid excretion (75-90%) Overproduction of uric acid (10-25%) Clinical…
Ethylene Glycol
Ethylene Glycol Shane M. Meehan, MBBCh Key Facts Terminology Oxalosis due to ethylene glycol ingestion Etiology/Pathogenesis Renal injury due to calcium oxalate deposition and other toxins like glycolic acid Clinical…
Glomerulocystic Disease
Glomerulocystic Disease Aleksandr Vasilyev, MD, PhD Anthony Chang, MD Key Facts Terminology 2-3x dilatation of Bowman space, > 5% of glomeruli in absence of other kidney diseases GCKD reserved for…
Dense Deposit Disease
Dense Deposit Disease A. Brad Farris, III, MD Key Facts Terminology C3 nephropathy with very electron-dense deposits within GBM and mesangium Clinical Issues Rare (1-3 cases/million) Primarily children 5-15 years…
