13: Metabolism and temperature regulation


 


3. A 54-year-old man consumes a meal containing a large amount of fat. At which of the locations in the following figure is bile salts most likely to be absorbed by an active transport process?
image

 

4. A 69-year-old woman has a 30-year history of alcoholism and liver disease. She visits her physician because of swelling in the abdomen. An increase in which of the following is the most likely cause of the ascites?

A) Hepatic artery pressure


B) Hepatic vein pressure


C) Hydrostatic pressure of peritoneal fluid


D) Plasma albumin concentration


E) Portal vein pressure

5. The first stage in using triglycerides for energy is hydrolysis of the triglycerides to which of the following substance(s)?

A) Acetyl coenzyme A and glycerol


B) Cholesterol and fatty acids


C) Glycerol 3-phosphate and cholesterol


D) Glycerol and fatty acids


E) Phospholipids and glycerol

6. Most of the heat loss from an unclothed person at room temperature occurs by which of the following mechanisms?

A) Conduction to air


B) Conduction to objects


C) Convection


D) Evaporation


E) Radiation

7. The increase in serum bilirubin levels in patients with alcoholic cirrhosis most often results from which of the following?

A) Decreased excretion of bilirubin into bile


B) Increased uptake of bilirubin by hepatocytes


C) Enhanced conjugation of bilirubin


D) Excessive hemolysis

8. A 65-year-old man has a 25-year history of alcoholism and liver disease. He visits his physician because of swelling in his legs. A decrease in which of the following is likely to contribute to the development of edema in his legs?

A) Capillary hydrostatic pressure


B) Femoral vein pressure


C) Interstitial fluid hydrostatic pressure


D) Liver lymph flow


E) Plasma albumin concentration

9. A 45-year-old African-American man is admitted to the emergency department because of upper right quadrant pain. The man has a history of sickle-cell disease. Laboratory tests show that plasma bilirubin levels are three times greater compared to normal. Ultrasound studies confirm the presence of gallstones. Which of the following is the most likely composition of the gallstones in this patient?

A) Bile pigments


B) Calcium


C) Cholesterol


D) Fatty acids


E) Sugar


Questions 10 and 11


Refer to the following figure to answer questions 10 and 11.


image

 

10. Abundant amounts of adenosine triphosphate (ATP) in the cytoplasm of the cell inhibit which of the following steps in glycolysis?

A) Conversion of glucose to glucose-6-phosphate


B) Conversion of fructose-6-phosphate to fructose-1,6-diphosphate


C) Conversion of 1,3-diphosphoglyceric acid to 3-phosphoglyceric acid


D) Conversion of phosphoenolpyruvic acid to pyruvic acid

11. Abundant amounts of adenosine diphosphate (ADP) or adenosine monophosphate (AMP) stimulate which of the following steps in glycolysis?

A) Conversion of glucose to glucose-6-phosphate


B) Conversion of fructose-6-phosphate to fructose-1,6-diphosphate


C) Conversion of 1,3-diphosphoglyceric acid to 3-phosphoglyceric acid


D) Conversion of phosphoenolpyruvic acid to pyruvic acid

12. The transport of glucose through the membranes of most tissue cells occurs by which of the following processes?

A) Facilitated diffusion


B) Primary active transport


C) Secondary active co-transport


D) Secondary active countertransport


E) Simple diffusion

13. Which of the following mechanisms causes heat loss from a normal person when the environmental temperature is 106°F and the relative humidity is less than 10%?

A) Conduction


B) Convection


C) Evaporation


D) Radiation

14. About 75% of the blood flowing through the liver is from the portal vein, and the remainder is from the hepatic artery during resting conditions. Which of the following best describes the liver circulation in terms of resistance, pressure, and flow?


 
image

 

15. A scuba diver explores an underwater lava flow where the water temperature is 102°F. Which of the following profiles best describes the mechanisms of heat loss that are effective in this man?


 
image

 


16. A 57-year-old obese woman on hormone replacement therapy develops gallstones. Her gallstones are most likely composed of which of the following substances?

A) Bile salts


B) Bilirubin


C) Calcium salts


D) Cholesterol


E) Free fatty acids

17. Deamination means removal of the amino groups from the amino acids. Which of the following substances is produced when deamination occurs by transamination?

A) Acetyl coenzyme A


B) Ammonia


C) Citrulline


D) Ornithine


E) α-ketoglutaric acid

18. Most of the energy released from the glucose molecule occurs by which of the following processes?

A) Citric acid cycle


B) Glycogenesis


C) Glycogenolysis


D) Glycolysis


E) Oxidative phosphorylation

19. A 30-year-old man runs on an inclined treadmill until near exhaustion for an experiment examining anaerobic exercise conditioning. All of the following statements concerning the conversion of pyruvic acid to lactic under anaerobic conditions are true EXCEPT one. Which one is this EXCEPTION?

A) Conversion of pyruvic acid to lactic acid provides a sinkhole into which the end-products of glycolysis can disappear


B) Pyruvic acid combines with NAD+ to produce lactic acid and NADH


C) The NAD+ produced by the conversion of pyruvic acid to lactic acid can combine with two hydrogen atoms and allow glycolysis to continue


D) Under the above conditions, the heart can use lactic acid as an energy source

20. A 45-year-old man is admitted to the emergency department after he was found lying in the street in an inebriated state. He is markedly pale with icteric conjunctivae and skin. His abdomen is distended, and there is shifting dullness, indicating ascites. The liver is enlarged about 5 centimeters below the right costal margin and tender. The spleen cannot be palpated. There is bilateral edema of his legs and feet. Which of the following values of direct and indirect bilirubin (in milligrams per deciliter) are most likely to be present in this man’s plasma?


 





 


 


 



 


 


 



 


 


 



 


 


 



 


 


 



 


 


 


  Direct Indirect
A) 1.1 1.2
B) 1.7 5.4
C) 2.4 2.5
D) 5.2 1.8
E) 5.8 7.2

 


Questions 21–23


Use the following figure to answer questions 21 to 23. The diagram shows the effects of changing the set-point of the hypothalamic temperature controller. The red line indicates the body temperature, and the blue line represents the hypothalamic set-point temperature.


image

 

21. Which of the following sets of changes occurs at point W, compared with point V?


 
image

 

22. Which of the following sets of changes occurs at point Y, compared with point V?


 
image

 


23. Which of the following sets of changes occurs at point X, compared with point V?


 
image

 

24. Which of the following is the most abundant source of high-energy phosphate bonds in the cells?

A) Adenosine triphosphate (ATP)


B) Phosphocreatine


C) Adenosine diphosphate (ADP)


D) Creatine


E) Creatinine

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Mar 25, 2017 | Posted by in PHYSIOLOGY | Comments Off on 13: Metabolism and temperature regulation

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