Xanthogranulomatous Cholecystitis

Xanthogranulomatous Cholecystitis

Laura Webb Lamps, MD

Xanthogranulomatous cholecystitis often features a markedly thickened wall with overlying mucosal ulceration. Note the associated cholesterol clefts image in the granulomatous inflammation.

Xanthogranulomatous cholecystitis is often characterized by a dense infiltrate of foamy histiocytes, many of which contain ceroid pigment. Multinucleated giant cells are also common image.



  • Xanthogranulomatous cholecystitis (XGC)


  • Cholegranulomas

  • Ceroid granulomas


  • Variant of chronic cholecystitis featuring florid proliferation of foamy macrophages and granulomatous reaction to bile

Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Xanthogranulomatous Cholecystitis

Full access? Get Clinical Tree

Get Clinical Tree app for offline access