Venous and Arterial Thoracic Outlet Syndrome

Venous and Arterial Thoracic Outlet Syndrome

Jason T. Lee


  • Most patients with vTOS are young, healthy, and often athletically inclined who present with the abrupt onset of unilateral arm swelling in their dominant arm after repetitive, strenuous use for sport, work, or recreation. Athletes affected can include baseball pitchers, rowers, swimmers, water polo players, weightlifters, volleyball players, surfers, football quarterbacks, or any others relying on repetitive upper extremity effort. The swelling is noted in the shoulder, arm, and hand and can be accompanied by aching, throbbing, or tightness that worsens with more activity. Because most patients are otherwise young and healthy, an orthopedic cause such as strain, muscle pull, or joint injury is often considered initially. Cyanosis of the affected extremity, visible chest wall venous collaterals, or progressively worsening symptoms suggest a vascular etiology, prompting referral to an interventionalist. On exam, the arm is swollen, tender to palpation, warm, and often has visible superficial collaterals that track onto the anterior chest wall (FIG 3). Range of motion of the affected extremity can be impeded due to patient discomfort.

  • aTOS patients will present with mild hand ischemia due to distal embolization, which manifests as digital ischemia or splinter hemorrhage. The diagnosis is often delayed due to the fact that these patients have no typical atherosclerotic risk factors and are mostly young and athletic. A pulsatile mass or bruit may be present in the supraclavicular fossa or a bony prominence in that region may hint toward a cervical rib or muscular abnormality. Symptoms often are gradual and unnoticed by patients until occurring more frequently or when complete thrombosis occurs and the patient presents with critical upper extremity ischemia.


  • Patients suspected of having vTOS should undergo duplex ultrasound of the affected area. Axillosubclavian venous imaging can be challenging due to the clavicle’s location as well as many of these patients being quite muscular. Color flow duplex, phasicity of flow with respiration, and augmentation with compressive maneuvers can all aid in confirming the diagnosis of deep venous thrombosis (DVT). An experienced vascular sonographer and interpreter can make the diagnosis with high accuracy based on duplex alone. Crosssectional imaging with magnetic resonance imaging (MRI) or computed tomography (CT) venography is rarely needed or indicated in the workup of vTOS. Catheter-based venography is the key confirmatory imaging study to document the extent of vTOS and leads to the initial recommended therapeutic strategy of thrombolysis and reduction of clot burden.

  • Patients presenting with digital ischemia suspicious for aTOS should undergo plain radiographic imaging to assess for a cervical rib (FIG 4). Digital plethysmography of bilateral upper extremities can be performed to visualize blood flow to each finger and can rule out Raynaud’s type etiologies in the differential diagnosis. Wrist-brachial indices should be documented prior to any further intervention to establish baseline flow characteristics. CT-A of the neck and upper extremity in provocative positioning (arms at 180 degrees overhead) provides the most definitive visualization of the affected region, confirming the presence of the cervical rib, delineating the amount of thrombus in the subclavian aneurysm, and documenting the proximal and distal vasculature for operative planning (FIG 5).

FIG 4 • Chest x-ray demonstrating left cervical rib (arrow).

FIG 5 • CT-A reconstruction of 19-year-old collegiate tennis player with cervical rib (arrows) that led to subclavian aneurysm formation. Patient presented with fingertip emboli after playing long matches.


Preoperative Planning

Jul 24, 2016 | Posted by in GENERAL SURGERY | Comments Off on Venous and Arterial Thoracic Outlet Syndrome
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