Transient Erythroblastopenia of Childhood

Transient Erythroblastopenia of Childhood

Kathryn Foucar, MD

Peripheral blood smear shows a profound normocytic/normochromic anemia without polychromasia. There is minimal, if any, anisopoikilocytosis of RBCs.

Bone marrow aspirate smear shows a marked decrease in the erythroid lineage with only rare erythroblasts image and no maturing forms. Granulocytic lineage is normal.



  • Transient erythroblastopenia of childhood (TEC)


  • Transient red cell aplasia


  • Idiopathic, self-limited red cell aplasia characterized by

    • Normocytic/normochromic anemia

    • Marked reticulocytopenia

    • Decreased erythroid lineage cells in bone marrow (red cell aplasia)


Multifactorial Causes

  • Unclear; usually no causative factor identified

  • Underlying viral infection or immune aberration postulated but not well documented

  • Usually not linked to constitutional or familial conditions

Jun 13, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Transient Erythroblastopenia of Childhood

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