Sclerotic Fibroma



Sclerotic Fibroma


David Cassarino, MD, PhD










Scanning magnification view shows a dermal-based nodular fibroblastic proliferation with storiforming of collagen.






Higher power magnification shows bland fibroblasts image and scattered inflammatory cells image in a dense fibrous stroma.


TERMINOLOGY


Synonyms



  • Storiform collagenoma


  • Pleomorphic sclerotic fibroma


Definitions



  • Benign, dermal-based fibroblastic proliferation with storiforming bundles of collagen


ETIOLOGY/PATHOGENESIS


Unknown



  • May be related to trauma


  • Some cases may represent regressed dermatofibromas


Genetic Syndrome



  • Multiple lesions are associated with Cowden syndrome, consistent with genetic influence

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Sclerotic Fibroma

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