Pseudomembranous enterocolitis
LIFE-THREATENING DISORDER
An acute inflammation and necrosis of the small and large intestines, pseudo-membranous enterocolitis usually affects the mucosa but may extend into submucosa and, rarely, other layers. Marked by severe diarrhea, this rare condition is generally fatal in 1 to 7 days from severe dehydration and from toxicity, peritonitis, or perforation.
Causes
Pseudomembranous enterocolitis is thought to be caused by a change in the flora of the colon and an overgrowth of a toxin-producing strain of Clostridium difficile.
Pseudomembranous enterocolitis has occurred postoperatively in debilitated patients who have undergone reabdominal surgery and in patients who