Mastectomy: Total (Simple), Modified, and Classic Radical
Total (sometimes called simple) mastectomy removes all the glandular tissue of the breast. It is sometimes required for treatment of extensive ductal carcinoma in situ. In combination with reconstructive surgery, bilateral total mastectomy is sometimes used for breast cancer prophylaxis in carefully selected patients.
Modified radical mastectomy adds the removal of the node-bearing tissue of the axilla while preserving the muscular contours of the upper chest wall. The operation was modified from the original or classic radical mastectomy to enhance the cosmetic result without compromising control of disease. Many modifications of the original classic radical mastectomy have been described. They differ in the extent of tissue removed and the completeness of axillary dissection. The modification described here combines a thorough axillary dissection with preservation of muscle contour. Other modified radical mastectomy techniques are detailed in the references.
Classic radical mastectomy is still used in those rare circumstances in which wider excision of the pectoral muscles might enhance local control. This is increasingly rare as better neoadjuvant chemotherapy has become available.
When mastectomy is performed for risk reduction (sometimes termed cancer prophylaxis) or for early disease, skin-sparing mastectomy with immediate reconstruction may be appropriate. Techniques applicable to that operation are mentioned throughout and references at the end give greater details on this evolving procedure. The procedure is also briefly discussed in Chapter 15.
Sentinel lymph node biopsy (see Chapter 18) is frequently combined with mastectomy. It may be performed through the lateral aspect of the incision or, if a skin-sparing technique is employed, through a separate axillary incision.
Steps in Procedure
Total Mastectomy
Position patient with arm out; may drape arm free if desired
Ellipse of skin including nipple-areolar complex and skin over tumor
Develop flaps at level of fusion plane between subcutaneous fat and fatty envelop of breast to sternum medially, clavicle superiorly, rectus inferiorly, latissimus laterally
Elevate breast from pectoralis major muscle from superior medial to inferior lateral
Take pectoral fascia for cancer
Leave pectoral fascia for immediate reconstruction with implant
Identify and ligate perforating branches of internal thoracic (mammary) vessels
Obtain hemostasis and close wound over two closed suction drains
Modified Radical Mastectomy
Develop flaps and dissect breast from pectoralis major muscle as described above
Leave breast attached at lateral aspect and use weight of breast to enhance retraction
Incise pectoral fascia at lateral edge of pectoralis major and elevate muscle
Dissect under pectoralis major muscle, removing all fatty node-bearing tissue
Preserve median pectoral nerve
Sweep fatty tissue laterally and expose and protect long thoracic nerve
Identify axillary vein and sweep fatty tissue downward
Ligate and divide thoracodorsal vein and preserve thoracodorsal nerve and artery
Sweep all fatty tissue downward and terminate dissection
Obtain hemostasis and lymph stasis and close over two closed suction drains
Dog Ear Correction by V-Y Flap Advancement
Close middle of incision
Elevate apex of dog ears to define pyramids of tissue
Excise triangles of redundant tissue
Suture the resulting reverse arrowheads in place
Record length of dog ear in operating note
Classical Radical Mastectomy
Position patient as noted, prep abdomen or thigh for possible skin graft
Develop flaps as previously outlined
Shave pectoralis major muscle (with overlying breast tissue) over chest wall from medial to lateral
Ligate perforating branches of internal thoracic (mammary) vessels as encountered
Similarly excise pectoralis minor muscle when exposed
Axillary dissection proceeds as previously outlined but includes level III nodes
Close as previously described, placing skin graft in midportion if required
Hallmark Anatomic Complications
Injury to long thoracic nerve
Injury to thoracodorsal nerve
Injury to intercostobrachial nerves
Injury to axillary vein
Seroma formation
List of Structures
Pectoralis major muscle
Pectoralis minor muscle
Subclavius muscle
Clavipectoral fascia
Coracoid process
Lateral pectoral nerve
Medial pectoral nerve
Thoracodorsal nerve
Long thoracic nerve
Axillary artery
Axillary vein
Thoracoacromial artery
Thoracodorsal vein
Internal thoracic (mammary) artery
Internal thoracic (mammary) vein
Axillary lymph nodes
Landmarks
Clavicle
Anterior rectus sheath
Latissimus dorsi muscle
Sternum
Total and Modified Radical Mastectomy
Position of the Patient and Choice of Skin Incision (Fig. 17.1)
Technical and Anatomic Points
The operation is performed under general anesthesia. After the initial intubation, muscle relaxants are avoided so that nerve function can be assessed. Position the patient supine, with the ipsilateral arm extended on an armboard. If necessary, place a small, folded sheet under the shoulder, to improve exposure. Avoid hyperextending the shoulder because this can cause neurapraxia. Drape the arm free so that it can be moved during the course of the dissection (Fig. 17.1A).
The choice of incision depends on several factors, including the location of the lesion, any prior biopsy incisions, and planned reconstruction. When immediate reconstruction is to be performed, design the skin incision in consultation with the plastic surgeon who will scrub in to do the reconstruction. In many cases, skin-sparing flaps can be created in such a manner as to be oncologically correct and yet provide an aesthetically pleasing outcome.
When delayed reconstruction is a possibility, a generally transverse incision is favored as it facilitates reconstruction. When reconstruction will not be performed, a generally oblique incision that is high at the axillary end and low medially provides excellent access. Flaps generally heal very well with this incision and the end result is a flat scar to which prostheses can easily be adapted.
The skin incision should include the nipple-areolar complex and the skin overlying the tumor, biopsy cavity, and any prior biopsy incision (Fig. 17.1B). The biopsy cavity is considered to be contaminated by tumor cells and frequently contains gross residual disease. It must be excised in its entirety as dissection progresses. Therefore, if the biopsy is performed through an incision located at some distance from the mass, a correspondingly larger amount of skin should be sacrificed. Alternatively, an ellipse of skin around the biopsy incision may be excised
separately. Do not compromise the skin incision because of fear of difficulty in closure. A skin graft will heal well over the underlying muscle and may be used if necessary. This is rarely necessary if flaps are designed properly.
separately. Do not compromise the skin incision because of fear of difficulty in closure. A skin graft will heal well over the underlying muscle and may be used if necessary. This is rarely necessary if flaps are designed properly.
Figures 17.1C and 17.1D show how a “lazy S” type incision provides flaps that can accommodate a variety of lesion locations, yet slide together to afford primary closure with minimal tension. The easiest way to create the lazy S is to first outline a diamond shape around the nipple areola and tumor location, then round the corners a bit. As the incision is closed, flaps are allowed to slide from side to side and from top to bottom as shown. The result is a flat scar that is hidden under clothing, even for some upper inner quadrant lesions.
Development of Flaps (Fig. 17.2)
Technical Points
Incise the skin and subcutaneous tissue. Visualize the breast as lying encapsulated in a separate layer of subcutaneous fat that lies 0.5 to 1.0 cm below the skin. Often, this layer can be defined as the skin incision is made. Place Lahey clamps on the dermal side of the upper flap and have an assistant place these under strong upward traction (Fig. 17.2A). Apply countertraction by pulling the breast tissue down and toward you strongly with a lap sponge. Avoid manipulating the breast overlying the biopsy site. Develop flaps by sharp dissection using a shaving motion with a sharp knife or electrocautery. If a knife is used, change blades frequently. Dissection in the proper plane is surprisingly bloodless. A network of large subcutaneous veins is often visible on the underside of the flap and will be preserved if dissection progresses in the proper plane. Ligate occasional bleeders on the underside of the flap. (Use electrocautery with caution on the flap because it can burn through the thin flap to damage the overlying skin surface.) Confirm the thickness of the flap by palpation as the dissection progresses.
An alternative technique uses slightly opened Mayo scissors to develop the flaps by a push-cut technique. This is particularly useful when the skin incision is small, as during skin-sparing mastectomy.
In the axilla, the skin flap will be crossed by hair follicles and apocrine glands. Divide these sharply. Raise flaps to the level of the clavicle superiorly, the midline medially, the anterior rectus sheath inferiorly, and the anterior border of the latissimus dorsi muscle laterally (Fig. 17.2B). Of these, the lateral border of the latissimus dorsi is generally the most difficult to find.
Identify this muscle by palpation of a longitudinal ridge of muscle tissue. Dissect sharply down to confirm its identity by visualizing longitudinal muscle fibers. Trace the muscle up toward the axilla. Check the upper flap for hemostasis and place a moist laparotomy pad under the flap. Place Lahey clamps on the inferior skin incision and develop the inferior flap by the same technique. The plane between breast and subcutaneous tissue is frequently less well defined inferiorly, and unless care is taken, the inferior flap may be cut too thick. Guard against this by constant palpation of the thickness of the flap. If white fibrous tissue (breast or suspensory ligaments of the breast [Cooper’s ligaments]) is seen, the flap is too thick and must be cut thinner.
Identify this muscle by palpation of a longitudinal ridge of muscle tissue. Dissect sharply down to confirm its identity by visualizing longitudinal muscle fibers. Trace the muscle up toward the axilla. Check the upper flap for hemostasis and place a moist laparotomy pad under the flap. Place Lahey clamps on the inferior skin incision and develop the inferior flap by the same technique. The plane between breast and subcutaneous tissue is frequently less well defined inferiorly, and unless care is taken, the inferior flap may be cut too thick. Guard against this by constant palpation of the thickness of the flap. If white fibrous tissue (breast or suspensory ligaments of the breast [Cooper’s ligaments]) is seen, the flap is too thick and must be cut thinner.
Draw a line around the margins of the dissection by incising the fascia at the perimeter of the field with electrocautery. This will prevent your dissecting too far in any direction. Recheck both flaps for hemostasis and place warm moist lap pads under them. Take care throughout the operation not to allow the subcutaneous fat of the underside of the flaps to become exposed and desiccated.
Anatomic Points
The breast is a conical ectodermal derivative limited to superficial fascia. The base of the breast overlies the chest wall from the second rib to the sixth and from the edge of the sternum to the midaxillary line. A lateral tongue of breast tissue—the axillary tail of Spence—extends into each axilla from the otherwise conical breast. This tail sometimes passes through the deep fascia of the axilla and approaches the pectoral group of axillary lymph nodes. Superficial to the breast is the superficial layer of the superficial fascia, whereas deep to the breast is the deep layer of superficial fascia. The subcutaneous fat lobules are small and easy to differentiate from the larger fat lobules of the breast itself.