Objectives
- List the accessory glands attached to the digestive tract by their ducts and describe their roles in digestion.
- Compare mucous and serous secretory cells in terms of their structure, staining, and secretions.
- Distinguish between the major salivary glands based on the content and distribution of serous and mucous cells.
- Relate pancreatic acinar cell ultrastructure to its function.
- Describe the liver’s double blood supply.
- Relate the hepatocyte’s complex ultrastructure to its many functions.
- Describe the boundaries and contents of the classic liver lobule, the portal lobule, and the hepatic acinus. Understand the functions that gave rise to these overlapping views of liver organization.
- Describe the structure, function, and location of the gallbladder.
- Identify the gallbladder in a micrograph and distinguish it from the small intestine.
- Identify and distinguish among digestive glands in micrographs; distinguish between adenomeres and ducts; and identify the different types of associated ducts, cells, and other substructures.
MAX-Yield™ Study Questions
1. Compare serous cells with mucous cells in terms of their secretory product, staining properties, and the type of alveoli they typically comprise (acinar or tubular) (II.B.1).
Contribution to salivary volume
Proportion of serous and mucous cells found in each gland
Presence of serous demilunes
Composition of their secretions
Presence of striated ducts (I.F.1.b)
4. Compare the saliva produced in response to sympathetic versus parasympathetic stimulation (II.G).
Acinar cells
Nuclei
RER
Golgi complex
Zymogen granules
Basal lamina
Lumen
Centroacinar cell
Intercalated duct
7. Describe two types of pancreatic exocrine secretion (III.B.1 and 2) in terms of their composition and role in digestion, the cells primarily responsible for their secretion, and the enteroendocrine hormone that stimulates their release.
9. Compare the exocrine pancreas with the parotid gland in terms of the chief secretory cell type (serous or mucous) (I.D), presence of centroacinar cells (III.B.2), islets of Langerhans (III.A), and striated intralobular ducts (I.F.1.b).
10. Name the two vessels that provide the liver’s blood supply (IV.A, C.1 and 2) and compare the blood they carry in terms of its origin (the vessels giving rise to those entering the liver), its contribution (%) to liver blood volume, and its oxygen, nutrient, and bilirubin content.
12. Sketch a cross-section of three adjacent classic liver lobules and include and label the following (Figs. 16–2 and 16–3):
Portal triads
Branches of the hepatic artery
Branches of the hepatic portal vein
Bile ducts
Central veins
Hepatic sinusoids
Space(s) of Disse
Hepatocytes
Endothelial cells
Kupffer cells
A portal lobule (outline)
A hepatic acinus (outline)
The direction of (use arrows):
Blood flow
Bile flow
Lymph flow
17. Name several proteins synthesized and secreted by hepatocytes (IV.D.1.b). Are these endocrine or exocrine products?
Protein synthesis and secretion (2.III.C.1.a and b)
Drug detoxification and inactivation (IV.D.1.b)
Synthesis of bilirubin glucuronide (IV.F.1.b)
Synthesis of bile acids (IV.F.1.a)
Storage of lipid (IV.D.3; 2.III.H)
Storage of glycogen (IV.D.1.b; 2.III.H)
19. Name the liver’s exocrine secretory product; describe its composition and function (IV.D.1.b and F.1).
20. List, in order, the named structures through which bile flows after secretion by the hepatocytes and name the segment of the digestive tract into which it is delivered (IV.F.2).
23. Compare the walls of the gallbladder with those of the small intestine in terms of the lining epithelium, mucosal branching, submucosa, and fiber orientation in the muscularis (V.A–C).