Fox-Fordyce Disease



Fox-Fordyce Disease


Michael W. Peterson, DO

Cary Chisholm, MD

Clay J. Cockerell, MD










Fox-Fordyce disease is characterized by grouped papules in the groin and, pictured above, the axilla. (Courtesy N. Agim, MD.)






There is a follicular plug image obstructing the follicle and eccrine duct ostium. There is a surrounding mild, perifollicular and periadnexal, lymphocytic infiltrate image.


TERMINOLOGY


Synonyms



  • Apocrine miliaria


Definitions



  • Keratin plugging of apocrine glands resulting in sweat retention and rupture of superficial apocrine duct


ETIOLOGY/PATHOGENESIS


Unknown



  • Multiple possible triggers



    • Hormonal factors


    • Emotional stimuli


    • Physical stimuli


Keratin Plugging of Apocrine Glands



  • Causes sweat retention


  • Ultimately distention and rupture of gland

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Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Fox-Fordyce Disease
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