Fibroepithelial Polyps (Acrochordons)
Elsa F. Velazquez, MD
Key Facts
Terminology
Skin tag, soft fibroma
Clinical Issues
Very common lesions
Usually affect adults
> 50 years old
Single or multiple
Neck, axilla, groin
Association with diabetes and obesity
Microscopic Pathology
Squamous epithelium
Loose to dense connective tissue with variable amount of blood vessels
Mature adipocytes may be present (fibrolipoma)
Top Differential Diagnoses
Seborrheic keratosis
Nevus lipomatosus superficialis
Pleomorphic fibroma
 Acrochordon characterized by a core of loose connective tissue devoid of adnexal structures  is covered by squamous epithelium  . |
 The fibrovascular core in this fibroepithelial polyp is composed of loose connective tissue with scattered vessels  and a few inflammatory cells. |
TERMINOLOGY
Synonyms
Skin tag, soft fibroma, fibrolipoma (with adipose tissue)
ETIOLOGY/PATHOGENESIS
May Be Associated with
Obesity
Colonic polyps (controversial)
Diabetes
Acromegaly
